Generic Name: Gemtuzumab Ozogamicin (gem TOO zoo mab oh zog a MY sin)
Brand Name: Mylotarg
Medically reviewed by Drugs.com. Last updated on Sep 27, 2020.
- Liver problems have happened with Mylotarg (gemtuzumab ozogamicin). Sometimes, this has been life-threatening or deadly. The chance of liver problems is higher in people who had a stem cell transplant before or after treatment with Mylotarg (gemtuzumab ozogamicin). It is also higher in people who have already had liver problems and in people getting higher doses of Mylotarg (gemtuzumab ozogamicin). Tell your doctor if you have ever had liver problems or a stem cell transplant.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
Uses of Mylotarg:
- It is used to treat a type of leukemia.
What do I need to tell my doctor BEFORE I take Mylotarg?
- If you have an allergy to gemtuzumab ozogamicin or any other part of Mylotarg (gemtuzumab ozogamicin).
- If you are allergic to Mylotarg (gemtuzumab ozogamicin); any part of Mylotarg (gemtuzumab ozogamicin); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are breast-feeding. Do not breast-feed while you take Mylotarg (gemtuzumab ozogamicin) or for 1 month after you stop Mylotarg (gemtuzumab ozogamicin).
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Mylotarg (gemtuzumab ozogamicin) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Mylotarg?
- Tell all of your health care providers that you take Mylotarg (gemtuzumab ozogamicin). This includes your doctors, nurses, pharmacists, and dentists.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. Rarely, some bleeding problems have been deadly.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- Talk with your doctor before getting any vaccines. Use of some vaccines with Mylotarg (gemtuzumab ozogamicin) may either raise the chance of an infection or make the vaccine not work as well.
- Infusion reactions have happened with Mylotarg (gemtuzumab ozogamicin). Sometimes, these could be very bad or life-threatening. Talk with the doctor.
- Infusion reactions can happen up to 24 hours after Mylotarg (gemtuzumab ozogamicin) is given.
- If you are 65 or older, use Mylotarg (gemtuzumab ozogamicin) with care. You could have more side effects.
- This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child.
- If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during treatment and for 3 months after your last dose.
- If you are a man and your sex partner gets pregnant while you take Mylotarg (gemtuzumab ozogamicin) or within 3 months after your last dose, call your doctor right away.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting Mylotarg (gemtuzumab ozogamicin). Talk with your doctor.
- Use birth control that you can trust to prevent pregnancy while taking Mylotarg (gemtuzumab ozogamicin) and for 6 months after stopping Mylotarg (gemtuzumab ozogamicin).
- If you get pregnant while taking Mylotarg (gemtuzumab ozogamicin) or within 6 months after your last dose, call your doctor right away.
How is this medicine (Mylotarg) best taken?
Use Mylotarg (gemtuzumab ozogamicin) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
- Other drugs will be given with Mylotarg (gemtuzumab ozogamicin) to help avoid side effects.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Stomach swelling or fast weight gain.
- Fever or chills.
- A fast heartbeat.
- A heartbeat that does not feel normal.
- Very bad dizziness or passing out.
- Shortness of breath.
- Not able to pass urine or change in how much urine is passed.
- This medicine can cause a severe bowel problem (neutropenic enterocolitis). This problem can be deadly, sometimes as early as the first day signs happen. Call your doctor right away if you have stomach pain with or without a fever, tender stomach, or diarrhea.
What are some other side effects of Mylotarg?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Mouth irritation or mouth sores.
- Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Mylotarg?
- If you need to store Mylotarg (gemtuzumab ozogamicin) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Mylotarg (gemtuzumab ozogamicin), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
- This information should not be used to decide whether or not to take Mylotarg (gemtuzumab ozogamicin) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Mylotarg (gemtuzumab ozogamicin). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Mylotarg (gemtuzumab ozogamicin). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Mylotarg (gemtuzumab ozogamicin).
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Mylotarg (gemtuzumab)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 2 Reviews
- Drug class: CD33 monoclonal antibodies
- FDA Alerts (1)
- FDA Approval History