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Doxylamine/ pseudoephedrine liquid

Generic Name: doxylamine/pseudoephedrine (dox-IL-a-meen/SOO-doe-e-FED-rin)
Brand Name: Lortuss LQ

Doxylamine/ pseudoephedrine liquid is used for:

Relieving symptoms of sinus congestion, runny nose, itching of the nose and throat, itchy or watery eyes, and sneezing due to colds, hay fever, and allergies. It may also be used for other conditions as determined by your doctor.

Doxylamine/pseudoephedrine liquid is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine and reducing symptoms such as watery eyes and sneezing. The decongestant relieves nasal congestion by causing vasoconstriction and shrinkage of the nasal mucous membranes and promoting drainage.

Do NOT use doxylamine/ pseudoephedrine liquid if:

  • you are allergic to any ingredient in doxylamine/pseudoephedrine liquid
  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you are unable to urinate or are having an asthma attack
  • you use any product containing diphenhydramine
  • you take droxidopa, sodium oxybate (GHB), or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using doxylamine/ pseudoephedrine liquid:

Some medical conditions may interact with doxylamine/pseudoephedrine liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of adrenal gland problems (eg, adrenal gland tumor), heart problems (eg, cor pulmonale; fast, slow, or irregular heartbeat; heart disease), high blood pressure, diabetes, blood vessel problems, a stroke, glaucoma or increased pressure in the eye, seizures, or thyroid problems
  • if you have a history of asthma or other breathing problems, chronic cough, lung problems (eg, chronic bronchitis, emphysema), chronic obstructive pulmonary disease (COPD), or sleep apnea
  • if you have a blockage of your bladder, stomach, or bowels; ulcers; trouble sleeping; an enlarged prostate or other prostate problems; or trouble urinating

Some MEDICINES MAY INTERACT with doxylamine/pseudoephedrine liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin or droxidopa because the risk of irregular heartbeat or a heart attack may be increased
  • Beta-blockers (eg, propranolol), furazolidone, linezolid, MAOIs (eg, phenelzine), sodium oxybate (GHB), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of doxylamine/pseudoephedrine liquid's side effects
  • Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by doxylamine/pseudoephedrine liquid
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by doxylamine/pseudoephedrine liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if doxylamine/pseudoephedrine liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use doxylamine/ pseudoephedrine liquid:

Use doxylamine/pseudoephedrine liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Doxylamine/pseudoephedrine liquid may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of doxylamine/pseudoephedrine liquid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use doxylamine/pseudoephedrine liquid.

Important safety information:

  • Doxylamine/pseudoephedrine liquid may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use doxylamine/pseudoephedrine liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using doxylamine/pseudoephedrine liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do not drink alcohol while you are using doxylamine/pseudoephedrine liquid.
  • If you have trouble sleeping, ask your pharmacist or doctor about the best time of day to take doxylamine/pseudoephedrine liquid.
  • Do not take diet or appetite control medicines while you are taking doxylamine/pseudoephedrine liquid without checking with your doctor.
  • Doxylamine/pseudoephedrine liquid has a decongestant and an antihistamine in it. Before you start any new medicine, check the label to see if it has a decongestant or antihistamine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 7 days; if they get worse; if they occur along with a fever, rash, or persistent headache; or if new symptoms occur, check with your doctor.
  • Doxylamine/pseudoephedrine liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to doxylamine/pseudoephedrine liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Doxylamine/pseudoephedrine liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking doxylamine/pseudoephedrine liquid for a few days before the tests.
  • Tell your doctor or dentist that you take doxylamine/pseudoephedrine liquid before you receive any medical or dental care, emergency care, or surgery.
  • Use doxylamine/pseudoephedrine liquid with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, dry mouth, excitability, low blood pressure, and trouble urinating.
  • Caution is advised when using doxylamine/pseudoephedrine liquid in CHILDREN; they may be more sensitive to its effects, especially excitability.
  • Doxylamine/pseudoephedrine liquid should not be used in CHILDREN younger than 6 years; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking doxylamine/pseudoephedrine liquid while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking doxylamine/pseudoephedrine liquid.

Possible side effects of doxylamine/ pseudoephedrine liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; confusion; difficulty urinating or inability to urinate; fast or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; mood or mental changes; persistent trouble sleeping; restlessness; seizures; severe dizziness, drowsiness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular breathing; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of doxylamine/pseudoephedrine liquid:

Store doxylamine/pseudoephedrine liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep doxylamine/pseudoephedrine liquid out of the reach of children and away from pets.

General information:

  • If you have any questions about doxylamine/pseudoephedrine liquid, please talk with your doctor, pharmacist, or other health care provider.
  • Doxylamine/pseudoephedrine liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take doxylamine/pseudoephedrine liquid or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about doxylamine/pseudoephedrine liquid. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to doxylamine/pseudoephedrine liquid. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using doxylamine/pseudoephedrine liquid.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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