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Generic name: Dextranomer and Hyaluronate Derivatives (Deflux) [ deks-TRAN-oh-mer-& hye-al-yoor-ON-ate-dah-RIV-ah-tives ]
Brand name: Deflux
Drug class: Miscellaneous uncategorized agents

Medically reviewed by Last updated on Jul 17, 2023.

Uses of Deflux:

  • It is used to treat backward flow of urine in the urinary tract (vesicoureteral reflux).

What do I need to tell my doctor BEFORE I take Deflux?

  • If your child is allergic to Deflux (dextranomer and hyaluronate derivatives (deflux)); any part of Deflux (dextranomer and hyaluronate derivatives (deflux)); or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
  • If your child has any of these health problem: Certain urinary tract problems (infection, Hutch diverticulum, ureterocele), kidney that does not work, or trouble passing urine.

This is not a list of all drugs or health problems that interact with Deflux (dextranomer and hyaluronate derivatives (deflux)).

Tell the doctor and pharmacist about all of your child's drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take Deflux (dextranomer and hyaluronate derivatives (deflux)) with all of his/her drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while I take Deflux?

  • Tell all of your child's health care providers that your child is taking Deflux (dextranomer and hyaluronate derivatives (deflux)). This includes your child's doctors, nurses, pharmacists, and dentists.

If your child is pregnant or breast-feeding a baby:

  • Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks to your child and the baby.

How is this medicine (Deflux) best taken?

Give Deflux (dextranomer and hyaluronate derivatives (deflux)) as ordered by your child's doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot.
  • The effect of Deflux (dextranomer and hyaluronate derivatives (deflux)) may not last forever. Your child may need this treatment again in the future.

What do I do if I miss a dose?

  • Call your child's doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child's doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
  • Not able to pass urine.
  • Cloudy or pink-red urine.
  • Stomach pain.
  • Fever.

What are some other side effects of Deflux?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child's doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

  • Stinging when passing urine.

These are not all of the side effects that may occur. If you have questions about side effects, call your child's doctor. Call your child's doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Deflux?

  • If you need to store Deflux (dextranomer and hyaluronate derivatives (deflux)) at home, talk with your child's doctor, nurse, or pharmacist about how to store it.

Consumer Information Use and Disclaimer

  • If your child's symptoms or health problems do not get better or if they become worse, call your child's doctor.
  • Do not share your child's drug with others and do not give anyone else's drug to your child.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. If you have any questions about Deflux (dextranomer and hyaluronate derivatives (deflux)), please talk with your child's doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.