Generic Name: carglumic acid (kar-GLOO-mik AS-id)
Brand Name: Carbaglu
Carbaglu is used for:
Treating high blood ammonia levels that are caused by the lack of a certain liver enzyme (N-acetylglutamate [NAG] synthase). It may be used along with other medicines or methods for lowering blood ammonia levels.
Carbaglu is similar to NAG, a substance that activates the process that removes ammonia from the blood. Carbaglu works by acting as a replacement for NAG in patients who cannot produce it on their own.
Do NOT use Carbaglu if:
- you are allergic to any ingredient in Carbaglu
Contact your doctor or health care provider right away if any of these apply to you.
Before using Carbaglu:
Some medical conditions may interact with Carbaglu. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
Some MEDICINES MAY INTERACT with Carbaglu. However, no specific interactions with Carbaglu are known at this time.
Ask your health care provider if Carbaglu may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Carbaglu:
Use Carbaglu as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Carbaglu by mouth immediately before meals.
- Do not swallow Carbaglu whole or crush the tablet.
- Mix each tablet in at least one-half teaspoon (2.5 mL) of water. The tablet may not dissolve completely. Swallow Carbaglu immediately after mixing.
- Rinse the container with water right away and swallow the rinse to be sure you receive the complete dose.
- Do not use any liquid other than water to mix Carbaglu.
- Check with your pharmacist about how to give Carbaglu if you will be using an oral syringe or a nasogastric (NG) tube.
- If you miss a dose of Carbaglu, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Carbaglu.
Important safety information:
- Avoid eating foods high in protein while taking Carbaglu. Follow the diet program given to you by your health care provider.
- Do NOT take more than the recommended dose without checking with your doctor.
- Lab tests, including blood ammonia levels, may be performed while you use Carbaglu. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Carbaglu should be used with caution in the ELDERLY; safety and effectiveness in elderly patients have not been established.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Carbaglu while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Carbaglu.
Possible side effects of Carbaglu:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; headache; nose or throat irritation; stomach pain; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); ear pain or discharge; fever or chills; increased sweating; loss of appetite; severe or persistent sore throat; unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Carbaglu:
Store unopened bottles of Carbaglu in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. After the bottle has been opened, do not refrigerate. Store opened bottles of Carbaglu at room temperature below 86 degrees F (30 degrees C) and away from heat, moisture, and light. Keep the bottle tightly closed. Do not store in the bathroom. Write the date of opening on the bottle. Throw away any medicine that is left 1 month after opening or if the expiration date on the bottle has passed, whichever is earlier. Keep Carbaglu out of the reach of children and away from pets.
- If you have any questions about Carbaglu, please talk with your doctor, pharmacist, or other health care provider.
- Carbaglu is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Carbaglu or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Carbaglu. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Carbaglu. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Carbaglu.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Carbaglu (carglumic acid)
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- During Pregnancy
- Dosage Information
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