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Carbaglu Side Effects

Generic Name: carglumic acid

Note: This document contains side effect information about carglumic acid. Some of the dosage forms listed on this page may not apply to the brand name Carbaglu.

For the Consumer

Applies to carglumic acid: oral tablet

Along with its needed effects, carglumic acid (the active ingredient contained in Carbaglu) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking carglumic acid:

More common
  • Chills
  • cough
  • decreased weight
  • diarrhea
  • fever
  • general feeling of discomfort or illness
  • headache
  • hoarseness
  • increased sweating
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • painful or difficult urination
  • pale skin
  • runny nose
  • shivering
  • sore throat
  • sweating
  • trouble sleeping
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking carglumic acid:

Symptoms of overdose
  • Fast, pounding, or irregular heartbeat or pulse
  • increase in mucous from the lungs
  • restlessness

Some side effects of carglumic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Change in hearing
  • change in taste
  • congestion
  • ear drainage
  • earache or pain in the ear
  • lack or loss of strength
  • loss of taste
  • rash
  • sleepiness or unusual drowsiness
  • stomach pain
  • stuffy or runny nose
  • swollen glands

For Healthcare Professionals

Applies to carglumic acid: oral tablet dispersible


Hematologic side effects have included anemia (13%) and decreased hemoglobin (13%).[Ref]


General side effects have included ear infection (13%).[Ref]


Gastrointestinal side effects have included abdominal pain (17%), diarrhea (13%), vomiting (26%), and dysgeusia (9%).[Ref]


Musculoskeletal side effects have included asthenia (9%).[Ref]


Metabolic side effects have included hyperhidrosis (9%), pyrexia (17%), anorexia (9%), and decreased weight (9%).[Ref]

Nervous system

Nervous system side effects have included headache (13%) and somnolence (9%).[Ref]


Immunologic side effects have included infection (13%), influenza (9%), nasopharyngitis (13%), pneumonia (9%), and tonsillitis (17%).[Ref]


Dermatologic side effects have included rash (9%).[Ref]


1. "Product Information. Carbaglu (carglumic acid)." Accredo Health Group Inc, Memphis, TN.

Some side effects of Carbaglu may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.