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Carbaglu Side Effects

Generic Name: carglumic acid

Note: This page contains information about the side effects of carglumic acid. Some of the dosage forms included on this document may not apply to the brand name Carbaglu.

For the Consumer

Applies to carglumic acid: oral tablet

In addition to its needed effects, some unwanted effects may be caused by carglumic acid (the active ingredient contained in Carbaglu). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking carglumic acid:

More common:
  • Chills
  • cough or hoarseness
  • decreased weight
  • diarrhea
  • fever or chills
  • general feeling of discomfort or illness
  • headache
  • increased sweating
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aches and pains
  • nausea
  • painful or difficult urination
  • pale skin
  • runny nose
  • shivering
  • sore throat
  • sweating
  • trouble sleeping
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting

If any of the following symptoms of overdose occur while taking carglumic acid, get emergency help immediately:

Symptoms of overdose:
  • Fast, pounding, or irregular heartbeat or pulse
  • increase in mucous from the lungs
  • restlessness

Minor Side Effects

Some of the side effects that can occur with carglumic acid may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Abdominal or stomach pain
  • change in hearing
  • change in taste
  • congestion
  • ear drainage
  • earache or pain in the ear
  • lack or loss of strength
  • loss of taste
  • rash
  • sleepiness or unusual drowsiness
  • stuffy or runny nose
  • swollen glands

For Healthcare Professionals

Applies to carglumic acid: oral tablet dispersible


Hematologic side effects have included anemia (13%) and decreased hemoglobin (13%).[Ref]


General side effects have included ear infection (13%).[Ref]


Gastrointestinal side effects have included abdominal pain (17%), diarrhea (13%), vomiting (26%), and dysgeusia (9%).[Ref]


Musculoskeletal side effects have included asthenia (9%).[Ref]


Metabolic side effects have included hyperhidrosis (9%), pyrexia (17%), anorexia (9%), and decreased weight (9%).[Ref]

Nervous system

Nervous system side effects have included headache (13%) and somnolence (9%).[Ref]


Immunologic side effects have included infection (13%), influenza (9%), nasopharyngitis (13%), pneumonia (9%), and tonsillitis (17%).[Ref]


Dermatologic side effects have included rash (9%).[Ref]


1. "Product Information. Carbaglu (carglumic acid)." Accredo Health Group Inc, Memphis, TN.

Not all side effects for Carbaglu may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.