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Bupivacaine and Epinephrine

Generic Name: Bupivacaine and Epinephrine (byoo PIV a kane & ep i NEF rin)
Brand Name: Marcaine with Epinephrine, Sensorcaine with Epinephrine, Sensorcaine-MPF with Epinephrine, Vivacaine

Warning

  • Do not use the 0.75% during labor. Unsafe side effects may happen. Talk with the doctor.

Uses of Bupivacaine and Epinephrine:

  • It is used to numb an area before care.
  • It is used before dental care to numb the area.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Bupivacaine and Epinephrine?

  • If you have an allergy to bupivacaine, epinephrine, or any other part of bupivacaine and epinephrine.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are taking any of these drugs: Dihydroergotamine, ergonovine, ergotamine, or methylergonovine.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take bupivacaine and epinephrine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Bupivacaine and Epinephrine?

  • Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how bupivacaine and epinephrine affects you.
  • If you have a sulfite allergy, talk with your doctor.
  • If you are 65 or older, use this medicine with care. You could have more side effects.
  • Do not give to a child younger than 12 years of age.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using bupivacaine and epinephrine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

Mouth:

  • Do not eat while your mouth feels numb. You may bite your tongue.

Spinal:

  • This medicine may cause short-term loss of feeling and motor activity in the lower half of your body. Do not try to get out of bed or do other tasks or actions until feeling and motor activity have returned to normal.

How is this medicine (Bupivacaine and Epinephrine) best taken?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Your doctor will give bupivacaine and epinephrine.
  • It is given as a shot into the skin or the spine.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • A heartbeat that does not feel normal.
  • Fast or slow heartbeat.
  • Change in balance.
  • Dizziness or passing out.
  • Restlessness.
  • Anxiety.
  • Change in speech.
  • Numbness or tingling in the mouth.
  • Metallic taste.
  • Blurred eyesight.
  • Ringing in ears.
  • Shakiness.
  • Twitching.
  • Low mood (depression).
  • Feeling sleepy.
  • Feeling confused.
  • Seizures.
  • Trouble breathing, slow breathing, or shallow breathing.

Spinal:

  • Trouble passing urine.
  • Loss of bladder or bowel control.
  • Change in sex ability.
  • Long-lasting burning, numbness, tingling, or paralysis in the lower half of the body.
  • Headache.
  • Backache.
  • Fever or chills.
  • Very upset stomach or throwing up.
  • Stiff neck.
  • If bright lights bother your eyes.

What are some other side effects of Bupivacaine and Epinephrine?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Side Effects (complete list)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Bupivacaine and Epinephrine?

  • If you need to store this medicine at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about bupivacaine and epinephrine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about bupivacaine and epinephrine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using bupivacaine and epinephrine.

Review Date: December 6, 2017

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