Generic name: Andexanet Alfa [ an-DEX-a-net-AL-fa ]
Brand name: Andexxa
Drug class: Anticoagulant reversal agents
Medically reviewed by Drugs.com. Last updated on Jan 30, 2023.
- Very bad and sometimes life-threatening side effects have happened within 30 days after getting andexanet alfa. This includes blood clots, heart attack, stroke, and sudden death. Follow what your doctor has told you about preventing these side effects after using andexanet alfa. If you have questions, talk with your doctor.
Uses of Andexanet Alfa:
- It is used to undo the effects of a certain blood thinner.
What do I need to tell my doctor BEFORE I take Andexanet Alfa?
- If you are allergic to andexanet alfa; any part of andexanet alfa; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take andexanet alfa with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Andexanet Alfa?
- Tell all of your health care providers that you take andexanet alfa. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Call your doctor right away if you have any bleeding after getting andexanet alfa.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using andexanet alfa while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Andexanet Alfa) best taken?
Use andexanet alfa as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given into a vein for a period of time.
What do I do if I miss a dose?
- This medicine is given on an as needed basis.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
- Cough that does not go away.
- Very bad dizziness or passing out.
- Very upset stomach or throwing up.
- Sweating a lot.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.
What are some other side effects of Andexanet Alfa?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling hot.
- Change in taste.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Andexanet Alfa?
- If you need to store andexanet alfa at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about andexanet alfa, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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- Drug class: anticoagulant reversal agents
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