Amphotericin B (Liposomal)
Generic Name: Amphotericin B (Liposomal) (am foe TER i sin bee lye po SO mal)
Brand Name: AmBisome
Medically reviewed by Drugs.com. Last updated on Jun 6, 2020.
Uses of Amphotericin B:
- It is used to treat fungal infections.
What do I need to tell my doctor BEFORE I take Amphotericin B?
- If you have an allergy to amphotericin or any other part of amphotericin B (liposomal).
- If you are allergic to amphotericin B (liposomal); any part of amphotericin B (liposomal); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are receiving a transfusion of a certain kind of white blood cell (leukocyte).
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with amphotericin B (liposomal).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take amphotericin B (liposomal) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Amphotericin B?
- Tell all of your health care providers that you take amphotericin B (liposomal). This includes your doctors, nurses, pharmacists, and dentists.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take amphotericin B (liposomal).
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Some people have had side effects during the infusion or a short time after treatment. Tell the doctor if you have a rash, redness, fever, chills, chest pain, shortness of breath, upset stomach, throwing up, or if you sweat a lot while getting amphotericin B (liposomal).
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using amphotericin B (liposomal) while you are pregnant.
How is this medicine (Amphotericin B) best taken?
Use amphotericin B (liposomal) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Chest pain or pressure or a fast heartbeat.
- Black, tarry, or bloody stools.
- Throwing up blood or throw up that looks like coffee grounds.
- Shortness of breath.
- Fever, chills, or sore throat; any unexplained bruising or bleeding; or feeling very tired or weak.
- Feeling confused.
- Blood in the urine.
What are some other side effects of Amphotericin B?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Constipation, diarrhea, stomach pain, upset stomach, throwing up, or feeling less hungry.
- Trouble sleeping.
- Back pain.
- Feeling tired or weak.
- Runny nose.
- Sweating a lot.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Amphotericin B?
- If you need to store amphotericin B (liposomal) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about amphotericin B (liposomal), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about amphotericin b liposomal
Other brands: AmBisome