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Aflibercept (Ophthalmic)

Generic Name: Aflibercept (Ophthalmic) (a FLIB er sept)
Brand Name: Eylea

Medically reviewed on Sep 5, 2018

Uses of Aflibercept:

  • It is used to treat macular degeneration.
  • It is used to treat macular swelling.
  • It is used to treat some eye problems caused by diabetes.

What do I need to tell my doctor BEFORE I take Aflibercept?

  • If you have an allergy to aflibercept or any other part of aflibercept (ophthalmic).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have an eye infection or swelling in the eye.
  • If you are breast-feeding or plan to breast-feed.

This is not a list of all drugs or health problems that interact with aflibercept (ophthalmic).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take aflibercept (ophthalmic) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Aflibercept?

  • Tell all of your health care providers that you take aflibercept (ophthalmic). This includes your doctors, nurses, pharmacists, and dentists.
  • Use care when driving or doing other tasks that call for clear eyesight.
  • Have your eye pressure checked. Talk with your doctor.
  • This medicine may raise the chance of very bad and sometimes deadly health problems caused by blood clots, like heart attack and stroke. Talk with the doctor.
  • This medicine may cause harm to the unborn baby if you take it while you are pregnant.
  • Use birth control that you can trust before care begins, during care, and for 3 months after care ends.
  • If you get pregnant while taking aflibercept (ophthalmic) or within 3 months after your last dose, call your doctor right away.

How is this medicine (Aflibercept) best taken?

Use aflibercept (ophthalmic) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Your doctor will give aflibercept (ophthalmic).
  • It is given as a shot into the eye.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • Chest pain or pressure.
  • Jaw pain.
  • Swelling, warmth, or pain in the leg or arm.
  • Change in eyesight, eye pain, or very bad eye irritation.
  • Eye redness.
  • Eyelid swelling.
  • If bright lights bother your eyes.

What are some other side effects of Aflibercept?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Seeing floaters.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Aflibercept?

  • If you need to store aflibercept (ophthalmic) at home, talk with your doctor, nurse, or pharmacist about how to store it.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about aflibercept (ophthalmic), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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