Generic Name: rabeprazole (ra-BEP-ra-zole)
Brand Name: Aciphex
Aciphex is used for:
Healing and maintaining healing of irritation of the esophagus. It is also used to treat symptoms of gastroesophageal reflux disease (GERD) (eg, heartburn). It may be used for short-term treatment of ulcers of the small intestine. It may be used with certain antibiotics to treat ulcers of the small intestine and to help prevent them from coming back. It may be used to treat conditions that cause your body to make too much stomach acid (eg, Zollinger-Ellison syndrome). It may also be used for other conditions as determined by your doctor.
Aciphex is a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.
Do NOT use Aciphex if:
- you are allergic to any ingredient in Aciphex or to similar medicines (eg, omeprazole)
- you are taking atazanavir, dasatinib, erlotinib, or rilpivirine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Aciphex:
Some medical conditions may interact with Aciphex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have low blood magnesium levels, low blood vitamin B12 levels or vitamin B12 deficiency, liver problems, or stomach or bowel cancer
- if you have osteoporosis (weak bones), a family history of osteoporosis, or other risk factors of osteoporosis (eg, smoking, poor nutrition)
Some MEDICINES MAY INTERACT with Aciphex. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood magnesium levels may be increased
- Anticoagulants (eg, warfarin), cyclosporine, diazepam, digoxin, methotrexate, phenytoin, saquinavir, or theophylline because the risk of their side effects may be increased by Aciphex
- Atazanavir, bosutinib, dasatinib, erlotinib, indinavir, itraconazole, ketoconazole, mycophenolate, nelfinavir, nilotinib, posaconazole, or rilpivirine because their effectiveness may be decreased by Aciphex
This may not be a complete list of all interactions that may occur. Ask your health care provider if Aciphex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Aciphex:
Use Aciphex as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Aciphex comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Aciphex refilled.
- Take Aciphex by mouth with or without food.
- Swallow Aciphex whole. Do not break, crush, or chew before swallowing.
- Tell your doctor if you cannot swallow tablets whole. You may need a different medicine.
- You may take antacids while you are taking Aciphex if you are directed to do so by your doctor.
- Continue to take Aciphex even if you feel well. Do not miss any doses.
- If you miss a dose of Aciphex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Aciphex.
Important safety information:
- Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
- Do NOT change your dose, stop taking Aciphex, or take Aciphex for longer than prescribed without checking with your doctor.
- Aciphex may increase the risk of a serious form of diarrhea. Contact your doctor right away if stomach pain or cramps, severe or persistent diarrhea or fever, or bloody or watery stools occur. Discuss any questions or concerns with your doctor.
- Aciphex may increase the risk of hip, wrist, and spine fractures in patients with weak bones (osteoporosis). The risk may be greater if you use Aciphex in high doses, for long periods of time, or if you are older than 50 years old. Contact your doctor if you have any questions about this information.
- Low blood magnesium levels have been reported rarely in patients taking proton pump inhibitors for at least 3 months. In most cases, this effect was seen after a year of treatment. If you will be taking Aciphex for a long time, or if you take certain other medicines (eg, digoxin, diuretics), your doctor may perform lab tests to check for low blood magnesium levels. Seek medical attention right away if you experience symptoms of low blood magnesium levels (eg, dizziness; fast or irregular heartbeat; involuntary muscle movements; jitteriness or tremors; muscle aches, cramps, pain, spasms, or weakness; seizures).
- Long-term treatment (eg, longer than 3 years) with medicines like this one has rarely caused low vitamin B12 levels. Discuss any questions or concerns with your doctor.
- Check with your doctor to see whether you should take a calcium and vitamin D supplement while you use Aciphex.
- Tell your doctor or dentist that you take Aciphex before you receive any medical or dental care, emergency care, or surgery.
- Use Aciphex with caution in the ELDERLY; they may be more sensitive to its effects, especially hip, wrist, and spine fractures.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Aciphex while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Aciphex, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Aciphex:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; gas; headache; mild diarrhea or stomach pain; mild sore throat.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody or watery stools; bone pain; chest pain; dizziness; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; involuntary muscle movements; joint or muscle aches or pain; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea, nausea, or vomiting; severe or persistent stomach or back pain; stomach cramps; swelling of the hands, ankles, or feet; symptoms of kidney problems (eg, not able to pass urine, change in the amount of urine produced, blood in the urine, a big weight gain); symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, unusual nausea, yellowing of the skin or eyes); tremors; unexplained weight loss; unusual bruising or bleeding; unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Store Aciphex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Aciphex out of the reach of children and away from pets.
- If you have any questions about Aciphex, please talk with your doctor, pharmacist, or other health care provider.
- Aciphex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Aciphex or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Aciphex. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Aciphex. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Aciphex.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Aciphex (rabeprazole)
- Other brands: Aciphex Sprinkle