No information is available on the amount of indapamide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over indapamide.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information on indapamide was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1-3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.
Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353–4.
2.
Reiher KH. Zentralbl Gynakol. 1963;85:188–90. [Suppression of lactation by stimulation of diuresis] [PubMed: 13973786]
3.
Stout G. Suppression of lactation. Br Med J 1962;1:1150. Letter. PMC1958377.
Substance Identification
Substance Name
Indapamide
CAS Registry Number
26807-65-8
Drug Class
Breast Feeding
Lactation
Antihypertensive Agents
Thiazide Diuretics
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