My doctor up my dosage from 50mg to 100mg, I'm a little nervous on taken the whole 100 because of the side effects. Been on sertraline for 8 weeks-4 weeks 25 mg - 4 weeks 50mg and now starting 100 mg. first few days on25 I thought I was gonna lose it because of the added anxiety but the doc prescribed me klonopin.5 which help a lot.