This is my fourth week on zoloft, I was given this for depressions and severe anxiety. My doctor gradually increased(?)the medication starting at 25, 50, 75 and last night I started on 100 mg. I just don't know whats going on, I will feel good for one day and then feel horrible the next day, I have had diarrhea since starting it, and feel overall weakness. Today I did have to take a xanax because I woke up panicking and I still feel horrible, could this be the zoloft? Will it get better? I have been to the Emergency room at least once a month due to my bad panic attacks, as I feel now I would go back, but I am beginning to wonder if I am just plain crazy, all the blood work comes back great..but I don't feel great... anyone have this same similar experience?