I have PTDS, anxiety,nocturnal wake up anxiety and depression.They have tried Celexa, Lexapro, Zoloft, Effexor, Wellbutrin but no combo's. I had the worst side effects with all of them unable to function or eat. Do not want to take Paxil as I heard its very hard to come off of. Have not tried Cymbalta, but have no Rx insurance. Does anyone know the cost? Currently on xanax 0.05 mg1x a day & 0.50 of Lorazepam for sleep. It works to just make the anxiety tolerable but does nothing for the depression & I do not want to become dependent. Now What do I do? I need something for both.