Taking linzess at night: what time and how long before it works?

Yes, it’s been my experience with its 290 dose, before dinner-gives me the desired outcomes. As early morning evaluations were unpredictable and created anxiety for me, e.g., will this process hinder my morning routines, will my process be slowed for some reason and I am delayed, etc. Taking prior my evening meal gives me more control.

I have been on Linzess for three months now, started withe 290and 145 mcg dosage. I have really chronic bowel issues but these are really harsh I find and can run you forever to the bathroom. I am on the 72mcg now and it really works but only if I take in early afternoon for relief by 8-9pm, which is okay by me. I didn’t get any relief with the before breakfast routine. I have decided to take it this way and I’m a happy camper.

I've been taking Linzess 72 for about 2 months. I had my gallbladder removed last September and it gave me severe constipation. The Doctor gave me the Linzess 144 mcg and it gave me diarrhea all the time. He switched me to the Linzess 72 and it worked better for me. I find that if I eat too much the 72 does not work as well and then I have to take the 144. I usually take the 72 at 6-7 AM and then after 30 minutes I eat something. After a hour or so I have a BM sometimes loose with diarrhea. I eat less at dinner and try to eat smaller portions for better results.

Can linzess be taken at bedtime

I just started the 145 mg. I don't usually eat a morning meal. I drink a meal shake and it doesn't seem to work very much. I've read your first meal should have fat in it to work. The main meal I eat with fat in it is supper. I've not experienced any of the diaherra from it. Should I try taking 30 minutes before I eat supper? Any advice welcome.

I just started taking this again, my second try at it. First, I took the 290, that caused me to go from one extreme to the other! But, now I’m going to try the middle dose. Thanks for the comments. I think I will start taking when I wake up in the middle of the night to go to the bathroom. Hopefully, it’ll be more effective, somewhat of an empty stomach and maybe it’ll work before I leave for work.

I have been on Linzess 290mg for over a month. Its starts 2 hours once you take it. I tried in the morning at 8am then I started taking it at 8pm 2 hours later I'm in the bathroom it can last up to 3 to 4 hrs. Believe me its midnight I'm still running to the bathroom I might take it as needed from now on. Cause I can not handle it. I hope that will help you out. There is never a good time to take it.

Warning: LOL if u take sleep meds and you take it at night prepare yourself and buy yourself some adult diapers

Can some one please explain to me how to take this at night... like do you not eat for a few hours before taking it? Thanks in advance!!

I just began linzess and was on the lowest dose- 75mg. No BM for 3 days, upped it to the 145mg (as per drs instructions) and finally had BM within 3 hrs of taking it at 9pm. However after the BM, I have violent diarrhea and then repeated small bouts all night and this morning. Have any of you had this happen? Now my tummy is gurgling and I’m not comfortable. Ugh.

I am new to taking a prescription for comstipafion. My doctor prescribed one 145 mg Linzess capsule daily. She told me to take it with my first meal of the day. (I see that this is not usually the prescribing directions). It has worked all right but I do not take it everyday. I am going to start taking it at night on the weekends to see if it works better taking it this way. I really appreciate are your replies. This is a sensitive subject for me, but I appreciate the site and being able “talk” to people who take Linzess and HOW they take it.

I take linzess right before I go to sleep any time from 10 pm and up.. I tried it right before I eat and it would cramp me and not work very well gurgling of water in my stomach. Now that I have switched to before bed time with a glass of water as soon as I wake up I have a bowel movement . I feel more regulated this way. I have also lost weight since I have taken it at night time.

I actually take Linzess between 2:00 am & 3:00 am daily. I get up at 5:00 am and by 5:30 am I am usually in the bathroom. While I am glad to be able to have a bm, it usually is violent diarrhea and I cannot always be guaranteed that by 7:30 am when I am due at work that it will have run its course.
The diarrhea was something I was willing to endure after months of pain and an inability to have any bm whatsoever, which also meant no appetite.
Unfortunately, Linzess has stopped working for me & I now have samples of Amitiza to try for a month.