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Which pill is stronger? M367 OR M363. Acetaminophen and hydrocodone?

6 Answers

Kyle92 3 June 2018

Well they are the same for the most part both are hydrocodone/acetaminophen 10mg. The only difference is the acetaminophen(tylenol) the pill that reads m367 is a 10/325. The pill the pill that reads m363 is a 10/500 meaning it contains more acetaminophen(tylenol). Which can be better for pain relief but also harmful if taken in large doses due to its harmful effects on the liver. Hope this help have a good one. ☺

Votes: +0
ahaggerty 15 Jan 2017

My opinion on this question is the m363 is stronger than m367,because m367 has more tylenol in the pill than hydrocodone, for the other one m363 has more hydrocodone in it and less Tylenol. Your welcome

Votes: +0
jlhailey 30 March 2017

I know its a little late but you got that backwards, but In my experience the 363 is better even though it is supposed to have the same amount of hydro as the 367. Don't know why but I get more relief from the 363 them than the 367

Mascony 7 July 2017

U got that backwards buddy

Mascony 7 July 2017

Jhailey maybe it's the Tylenol working for u

Lmounce 31 Oct 2016


Votes: +0
medmajorchris 26 July 2013

Technically these pills are the same strength. User "caringsonbj" is correct in saying that M367 has a hydrocodone-to-apap (paracetamol/acetaminophen) ratio of 10/325 and M363 has a ratio of 10/500, but hydrocodone is the primary drug in this prescription medication, so regardless of the amount of acetaminophen, the strength of this medication is clinically rated the same. And he is ALSO correct in saying that the maximum daily dosage of acetaminophen (paracetamol) is 4000mg (4g); anything higher than that can cause very serious-even fatal-liver issues, so tell your doctor that you would PREFER to have Norco 10s (which is what a M367 is) because of the 10/325 dosage. Lower doses of acetaminophen is ideal ;-) Hope this was insightful.

Votes: +0
PaidToPllay 16 Jan 2014

I completely agree with this post. Clinical reseach shows the addtional acetaminophen does nothing to increase the effectiveness of the hydrocodone. Research also shows that more than 2500 mg's of acetaminaphen can harn the liver.

As of 1/1/14, hydrocodone with 500 mg's of acetaminophin will be very hard to come by. Where I work, we replaced ALL hydro/aceta with x/325 instead of x/500. And always take exactly as prescribed.

drmemory 29 April 2017

"the maximum daily dosage of acetaminophen (paracetamol) is 4000mg (4g); anything higher than that can cause very serious-even fatal-liver issues"

My friend took too many and overdosed on these things, and even though he had the wits to call the ambulance, he didn't live long enough to get to the hospital.

caringsonbj 18 March 2011

the pill M367 is hydrocodone 10mg with 325mg acetaminophen whereas the M363 has hydrocodone 10mg with 500mg acetaminophen which make the M363 stronger because it has a stronger dose of the acetaminophen (Tylenol) in the medication combination. Please be careful about the use of acetaminophen and do not use more than 4000mg/per 24 hours.

Votes: +3
Rajive Goel 18 March 2011

M363 seems to be stronger than M367, however please double check it with a doc/pharmacist.

Votes: +0 free discount card

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