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Which pill is stronger? M367 OR M363. Acetaminophen and hydrocodone?

Answers (3)

Rajive Goel 18 Mar 2011

M363 seems to be stronger than M367, however please double check it with a doc/pharmacist.

caringsonbj 18 Mar 2011

the pill M367 is hydrocodone 10mg with 325mg acetaminophen whereas the M363 has hydrocodone 10mg with 500mg acetaminophen which make the M363 stronger because it has a stronger dose of the acetaminophen (Tylenol) in the medication combination. Please be careful about the use of acetaminophen and do not use more than 4000mg/per 24 hours.

medmajorchris 26 Jul 2013

Technically these pills are the same strength. User "caringsonbj" is correct in saying that M367 has a hydrocodone-to-apap (paracetamol/acetaminophen) ratio of 10/325 and M363 has a ratio of 10/500, but hydrocodone is the primary drug in this prescription medication, so regardless of the amount of acetaminophen, the strength of this medication is clinically rated the same. And he is ALSO correct in saying that the maximum daily dosage of acetaminophen (paracetamol) is 4000mg (4g); anything higher than that can cause very serious-even fatal-liver issues, so tell your doctor that you would PREFER to have Norco 10s (which is what a M367 is) because of the 10/325 dosage. Lower doses of acetaminophen is ideal ;-) Hope this was insightful.

PaidToPllay 16 Jan 2014

I completely agree with this post. Clinical reseach shows the addtional acetaminophen does nothing to increase the effectiveness of the hydrocodone. Research also shows that more than 2500 mg's of acetaminaphen can harn the liver.

As of 1/1/14, hydrocodone with 500 mg's of acetaminophin will be very hard to come by. Where I work, we replaced ALL hydro/aceta with x/325 instead of x/500. And always take exactly as prescribed.

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