When is the best time to apply moisturizer after applying eufedex, 10, 15 minutes?

Morning and evening is the best time of day to use Efudex or as instructed by your physician. Patients are advised not to use cosmetics or any other skin products, including creams, lotions, and medications, while on efudex therapy unless instructed by their doctor. See: https://www.drugs.com/cons/efudex-topical.html