I'm extremely sensitive to meds and usually start all my "new" scripts with 1/4 recommended physician dosage and work my way up. That's ok for most conditions however I have a UTI and my "new" family doctor ordered 500 mg. (twice a day) CIPRO for UTI for 3 days. I asked him for lowest dose (but have learned not all docs pay attention to this) so I asked the pharmacist who said I was given the "Normal" dose for UTI. Naturally and understandably the pharmacist said I shouldn't lower the dosage for anti-biotics. None-the-less, my nurse's medication guide claims that the "Normal" dosage for UTI is 250 or 500 mg (both twice a day). Has anyone had success with the lower 250 mg tabs?