Xyzal (levocetirizine) is the R-enantiomer of cetirizine, and is thus as such not a new compound, but part of an already known preparation. Cetirizine consists of equal parts R- and S-enantiomer, but several studies have shown that the pharmacological effect – a selective inhibitory effect on the peripheral H1 receptors – is induced by the R-enantiomer alone.
Xyzal tablets contain 5 mg levocetirizine, which corresponds to the content of active R-enantiomer in one 10 mg cetirizine tablet.
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