What should I avoid while taking Zyvox?
Avoid eating large quantities (over 100 mg tyramine per meal) of foods or beverages with high tyramine content should be avoided while taking Zyvox. Foods high in tyramine content include those that may have undergone protein changes by aging, fermentation, pickling, or smoking to improve flavor, such as aged cheeses (0 to 15 mg tyramine per ounce); fermented or air-dried meats (0.1 to 8 mg tyramine per ounce); sauerkraut (8 mg tyramine per 8 ounces); soy sauce (5 mg tyramine per 1 teaspoon); tap beers (4 mg tyramine per 12 ounces); red wines (0 to 6 mg tyramine per 8 ounces). The tyramine content of any protein-rich food may be increased if stored for long periods or improperly refrigerated
Avoid using the oral suspension formulation if you have problems breaking down amino acids as it contains about 20 mg of phenylalanine(an essential amino acid (a building block for proteins in the body, meaning the body needs it for health but cannot make it. You have to get it from food)
What are possible food and drug interactions associated with Zyvox?
If Zyvox is taken with certain food and other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zyvox with the following: buspirone, dopamine, dobutamine, epinephrine, isocarboxazid, meperidine, norephinephrine, phenylpropanolamine, phenelzine, pseudoephedrine, serotonin 5-HT1 receptor antagonists (such as sumatriptan, zolmitriptan), serotonin reuptake inhibitors (such as citalopram, fluoxetine, paroxetine), tricyclic antidepressants, tyramine.
TYRANAMINE-rich foods (PLEASE READ THOUROUGHLY)
These include Parmesan, romano, asiago, aged cheddar and other strong-tasting hard cheeses. While there are some, such as cream cheese and cottage cheese, that have little to no notable amounts of tyramine, most aged cheeses have high concentrations of tyramine, is a condition that is commonly associated with the usage of monoamine oxidase inhibitors (MAOIs), a class of anti-depressants. It is caused by a buildup of tyramine after the inhibition of MAO-A(can increase the sensitivity to tyramine if taken orally) or MAO-B( same as A) at high enough levels.
Avocados contain tyramine, especially overripe fruit. Avocados, when eaten in moderate quantities, generally do not have noticeable effects, provided that the fruit is not overripe. Banana peels contain significant levels of tyramine and dopamine.
All other fruits may contain tyramine, especially overripe and dried fruit. Common fruits that may contain significant levels of tyramine include eggplant, figs, grapes, oranges, pineapples, plums, prunes, and raisins.
Many processed foods contain high tyramine levels. A few processed foods that contain high amounts of tyramine include, but are not limited to, yeast extract, sauerkraut, and shrimp paste.
Meat and fish
Fresh liver, meat, and fish have no significant levels of tyramine, but matured liver and meat contain high amounts. Traditionally, meat from game birds and wild animals is hung in a cool place to improve flavour and tenderness, but this significantly increases the tyramine content. Processed meats, cured or pickled meats, and meat by-products and broths often contain significant amounts of tyramine.
All soy products (but mainly fermented soy products)contain high levels of tyramine. Aside from soybeans themselves, commonly consumed soy products include soy sauce, tofu, miso, and teriyaki sauce.
Nuts and chocolate
Chocolate does not contain appreciable amounts of tyramine, but does contain other active ingredients that are potentiated by MAOIs, such as phenethylamine. Accordingly, high quantities of chocolate may lead to nausea and headaches.
There is some evidence that great amounts of nuts, peanuts, coconuts, and brazil nuts may trigger hypertensive reactions and headache.
I hopes this helps ... from a caring individual
While eating small amounts of foods that are rich in vitamin K shouldn't cause a problem, avoid eating or drinking large amounts of:
Certain drinks can increase the effect of warfarin, leading to bleeding problems. Avoid or drink only small amounts of these drinks when taking warfarin:
- Zyvox Information for Consumers
- Zyvox Information for Healthcare Professionals (includes dosage details)
- Side Effects of Zyvox (detailed)
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