Wellbutrin - Have any of you experienced sever canker sores or mouth ulcers on this medication?

I've been online for quite some time trying to figure out why I've suddenly acquired a few small but painful sores in my mouth. Two are small sore spots on my tongue, one on my gumline and one on the inside of my lower lip. Reddened areas with white. Very sore and difficult to eat. I finally looked up Wellbutrin and mouth sores and found this question and responses. I started taking Wellbutrin 75mg (trying to work up to 150mg) about 8 days ago. I pretty much started getting sores immediately..with a new one last night.
Also my mouth is dry a lot and I keep moving my tongue around/against the inside of my lower teeth as well as a suction type thing with my lower lip and cheeks (suction happens mostly at night but during the day too). I'm a bit relieved I found this, but now not sure about the med. I'm hoping it will stop. I've been swishing salt water which seems to help a little... but not quite getting rid of the sores yet...

I am on 100mg Wellbutrin. A few months ago, I started getting more frequent canker sores. Also sores on tongue I often can't see. Saw a dental dermatologist who diagnosed my situation being caused by the Wellbutrin. He prescribed Dexamethasone mouthwash. Started to not help enough, so he added some ointments - one for cankers, the other for my tongue. Not always helping enough with the cankers, I bought OTC Zilactin which possibly has side effects. It creates a strange film over the sore but SO worth it helping even more! Hope this is helpful to someone because I have days where the pain is all I can think about!

I'm struggling with mouth sores... i cant eat and they hurt so bad. I started Wellbutrin and it has not been a week .

My mouth sores have been so bad, I was sent to an oncologist for an oral cancer biopsy. They removed an entire lesion. The pain from that was horrible!!! I have been to the doctor repeatedly trying to get answers to my swollen tongue, mouth sores, sore throat, etc. Had no idea it could be from her putting me on Wellbutrin. I’m glad to find out I’m not dying & just need to wean off this med.

I’m so happy to see these posts! I’ve been taking the medication for a month and a half. The pain under my tongue, in the back near my jaw/under the chin near the jawline has been terrible. I went back to my doctor who basically said maybe I had an ulcer about to form because he couldn’t see anything but I knew this is more than that. It hurts to talk, swallow, to eat and even turn my head. I feel so validated seeing that I was right and it’s related to this medication! Thank you!

Yes i have lots of canker sores which i attribute to wellbutrin. i've found this med to be enormously helpful so i'm going to continue to use it but this side effect is unfortunate. i've tried using a baking soda paste and rinsing with salt water to alleviate the symptons. Maybe i'll decrease from 150mg to 100mg to see if that reduce this annoying symptom.

Wow. I am reading the responses here and it is amazing that I am not alone. I have never had canker sores in my mouth but I get random painful areas on my tongue, tonsils, base of my tongue and inside my cheeks. My understanding is that Bupropion decreases saliva production and causes dry mouth which in turn, over time, causes a lot of issues like ulcers and oral pain. My major problem so far has been the salivary glands... lack of saliva clogs the salivary gland ducts in my mouth and as a result I get random one sided swelling of the neck and terrible jaw pain on that side. (The glands are right under the lower jaw bone and pain resembles deep tooth pain). Right now I am dealing with a painful spot at the base of my tongue (under the tongue and right next to the wisdom teeth)... it feels like I burned it with hot food... It is nerve racking... I am almost certain it is Bupropion but I am seeing an ear and nose specialist just to rule out other causes like infection or even cancer:(

Boy am I glad to find this thread!!! I have been taking Wellbutrin 150mg XL for about two years and have been experiencing mouth ulcers on the inside of my lips (mostly lower) cheeks and tongue (nothing more painful that a sore at the tip of your tongue

A few years late to answer, but yes. I’ve been on 150mg of Bupropion XL for less than a week and i’ve already developed multiple large painful sores on the inside of my lip and under my tongue. No home remedies like swishing with salt water or even OTC pain relief has helped. And the dry mouth side effect that comes with wellbutrin isn’t helping

I have been taking Wellbutrin for a couple of months and suddenly developed a horrible sore on my tongue that is one of the most painful things I’ve ever had. I have had a mouth ulcer before but this is worse than that. I have had it for about 10 days. To be honest, I prayed today for answers and tonight it came to me to read up on this medication. While I’m not happy others have had this side effect, at least I know it’s not just me. I’ve rinsed with warm salt water which is soothing but has not affected the severity at all. I will not be taking another pill and hope this goes away soon.

Yes, very shortly after taking Wellbutrin I started getting canker sores on my tongue, throat, and roof of my mouth. After putting up with it for about a month, I decided to stop taking it and the sores cleared up just days later.

From the literature and the product insert that comes with your prescription:

"Common (1% to 10% of users): Mouth ulcer, stomatitis

Uncommon (0.1% to 1% of users): Gingivitis, gum irritation, increased salivation, oral edema, toothache"

Yes

I was prescribed Wellbutrin to help quit smoking. As soon as I was weaned up to the full dose I got what I called Zombie Mouth. It looked and felt like the flesh in my mouth was falling apart like paper mache. It was AWFUL!!! I quit taking it, my mouth healed, and I am fine now but the experience was painful.