I have had four 10mg doses and have been in bed all weekend,with a headache. Not sure if this side effect will pass or if I should,call my doctor. Taking for MDD
Trintellix - Headache side effects?
Question posted by nitaj001 on 3 Oct 2016
Last updated on 8 September 2019 by Kenneth Rakestraw
I had headaches for 4 or 5 days at 5mg. They we t away.
I have been getting headaches a few days after I stopped taking Trintellix and nausea and dizziness.
This happened after taking them for almost 2 weeks and the dosage was 5 mg and was supposed to be increased to 10 mg after one week but I decided to stop taking them because I don't like the way they make me feel.
I hope that you are starting to feel better now.
Headaches are one of the most common side effects of Trintellix (and most antidepressants):
Very common (10% or more of users): Headache (up to 14.7%)"
The good news is:
"Side effects have been reported to be generally mild and transient. They are most common during the first 2 weeks of treatment and decrease in intensity and frequency with continued treatment. They generally do not lead to treatment cessation."
You should always let your doctor know if you're having side effects, but they do generally resolve on their own... and quickly.
I took my first dose of trintellix yesterday at about 3. Around 5 I got a bad headache and have had it since. Today when I took my next dose at around noon, about 20 mins after my headache increased and I got a giant wave of nausea. I hope my body gets used to this med and that it works, as I am almost out of other options.
In all of my 60 years, I have NEVER even had one migraine. Also, headaches overall have been virtually non-existent. But sometime after the onset of taking Trintellix (that replaced the maximum dose of Viibryd, which did not effectively treat my depression), I developed severe, debilitating migraines (with all the classic symptoms). So, I started breaking the tablet in half but still had the same migraines.
Today, I held off on taking all of my a.m. meds except Viibryd (to replace Trintellix), and no migraines. It is just after the noon hour (without headaches so far today), and I will now take the rest of my a.m. meds. This may not be the complete answer for me, but it was certainly an instant result. And I know that some will be critical for experimenting with my medications absent professional consultation, but my psyche doctor only has time to see me about only 4 to 6 months.
And my neurologist pointed to medication interaction as the root of several other issues I have been experiencing, referred me to a local psychiatrist as the only professional in the area that he was confident could address my situation. But he will not have an opening for me in a full 6 months.
Now that I seem to come upon the answer, I am going to call into my GP to get a med change.
I've been taking the same dose for MDD also for about three weeks. I'm very "headache sensitive" : migraines. This med has Not increased my headaches, it's actually seems to help. Give it more time. Maybe it's the change in seasons? Give it a few more days then call doc. Good luck.
- Trintellix uses and safety info
- Trintellix information for Healthcare Professionals (includes dosage details)
- Side effects of Trintellix (detailed)
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