Trintellix - Best time to take Morning or Bed time?

Tried the AM dosing and was going back to sleep until 12-1 pm! So much for being a morning person! Now take the pills after dinner at about 8:30pm. By 11 I’m asleep without any other meds for sleep. I wake up at about 6:30am with no drug hangover etc.

BTW - for me Trintellix took almost two months to become effective but when it did the change was amazing and the depression just lifted! It’s been almost seven months now and so far it’s amazing!

I take mine in the morning,
Never had any issue with nausea
Hope this helps :-)

I was always nauseous when I took it in the morning. Taking it at night is great! It's been over a month now, and I'm having better days.

I started off taking mine at bedtime. But for some reason, I would wake up too early in the morning, and have trouble going back to sleep. When I tried taking it first thing in the morning, I would get nauseated (I don't eat breakfast). I started taking it at noon after lunch and it works like a charm!
So, I guess you just have to try different times and see which one works best for you!

I was started on the 10mg of Trintilix 2 days ago... the first day I took it when I got it around 3pm... by 7pm, I could not stay awake and around 11 hours I was wide awake (2am) , severe nausea and vomited. Later in the morning around 10 am I took the 2nd dose... it’s 2am and I’m wide awake but no nausea or vomiting. I’m going to take my dose now as if it’s bedtime, and hopefully I will get squared away on it... I pray so. My doc and several friends say once it kicks in and is therapeutic, it works wonderfully... I’m praying for us all..
Blessings,❤️

I take it in the morning because it doesn't make me sleepy. First few weeks I had headache and nausea but it went away

Bedtime. No nausea. Easier for me to remember to take. Plus, you can take it on an empty stomach.