Hi everyone, I've been put on topamax to hopefully assist with weight loss as am obese and am really struggling with food. I've just titrated up to 75mg (25 in morning and 50 at night) and have so far found no changes in appetite and no weight loss. I realise weight loss is only a possible side effect, but I was so hopeful about this drug helping me! My question is, have people found that appetite suppression starts at a certain dose? Or do u think its too early? OR am I just one of those for whom topamax isn't working? Thankyou :)
Topamax weight loss side effect: dosage?
Question posted by Jess6702 on 15 Nov 2014
Last updated on 11 April 2023
This question has also been asked and answered here: Does topiramate cause weight loss?
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85 Answers Page 4
I've been on 25MG 2x day for a month and have lost 15 lbs. Titrating up to 50 MG 2x a day now.
I began taking Topiramate 25mg (the generic form) about 4 months ago for a different medical condition (tremors) and was told that weight loss may also be a side effect. Which was good news as I am also obese.
I did not think of this over the next few weeks, but while being weighed at another doctors appointment, I found that I had lost 20 lbs. I assumed that this could have been contributed to the scale being calibrated slightly different, my clothing had changed from winter to spring and I may have lost a few lbs. Either way, I was pleased.
Last week I returned to the prescribing doctors office and found that I had lost 30 lbs since my prescribing visit. All this time I gave little effort to losing weight, but found my appetite had decreased and I was not wanting or craving more of anything in particular.
My doctor has increased my dosage to 50mg; 25mg AM & 25MG PM. I am hopeful it will reduce my tremors more as well as decrease my appetite.
So, to get to your question, My appetite suppression began at the low dose of 25 mg. And it began within the first 4 months.
Hello, I am currently on Topamax (topiramate) 50mg twice a day. I have def noticed a weight loss. But I leveled out at about 35lbs total of weight loss. I started at 265lbs and the lowest I have been is 229lbs. I have not changed anything else in my life beside this so I have to contribute the weight loss to topamax.
I was prescribed topamax in February. I only took it for a few weeks because it took away my complete appetite. I couldn't even drink coffee. Water only. Within that first week is when I noticed I couldn't eat anything. I kept with it, hoping my body would adjust to a new med . After my 2nd week, I flushed it.
I'm those 2 weeks-actually 3 because it took a week to leave my system, i lost over 20 pounds
I lost 116 pounds on 100 mg a day in a year on Topamax! It was simply miraculous! I had gained so much weight on a lot of different depression meds and this was the only one that worked! When I got off of it, I gained 77 pounds! I recently am back on it and am hoping for the same or even better results. Wishing you all the best!
Ive been on topamax now for 5 years after the first year all if any side effects disappeared. I am taking 200mg bd for epilepsy and was hoping to have weight loss but no luck. I was having no luck with other meds and topamax came through for me but I understand 50% of people struggle with its side effects. It is worth trying and give it a while if you can for your body to adjust to it.
Yes! I would increase the dose. I was on 200 mg/ day and lost 50lbs in about 6 months. My doc has increased my dose, due to my cravings for alcohol starting to come back. I am hoping it make the alcohol cravings go away completely again, the weight loss is an AWESOME AND MUCH NEEDED SIDE EFFECT but I am taking it to help me stop drinking. I hope it helps both of us!! Good luck!
Topiramate side effects :
I started taking topiramate for complex migraines in Sept 16, at 50mg and gradually up to 100mg a day for 6 months. The side effects I had at that dosage was pins and needles, slight memory loss, eye sight blurry and I'd lost around stone and half. Then around January 2017 I had a bad migraine attack which caused another 'stroke effect' ( have these regular but this was a bad one ) the doctor upped the topiramate up to 200mg a day. Well, after around 4 days the nightmare started. I collapsed twice had two attacks in 24 hours pins and needles allover my body, off balance, memory loss fogginess I didn't know what day it was. Went to the doctors and he is weaning me off them to go on Gabapentin. Weaning off Topiramate is no walk in the park I am on 50/50 at the moment in 3 days I'm om 50/0 .. I know this is not PC but I thought I was going to end up in the nutty farm last week it was horrendous.
I genuinely thought I was losing the plot. Please do not use them to just lose weight. It is scary the memory loss and and the thoughts you think. It is not worth it.. Believe me Xxx
I am on 100mg in the morning and 100mg at night. It has taken about 2 months for me to really start noticing the weight loss but it seems like my loss is slower than others on here have been seeing. It does seem like I read tho that weight loss typically starts when you are on 100 - 200mg per day so you may talk to your doctor about increasing your dosage. Good Luck!!
PS. I do experience a lot of the negative side effects... I have terrible pressure in my eyes that has been causing some pain and slight occasional blurred vision, stomach pain, not nausea, just pain, extreme fatigue. But the positive benefits are out weighing the negative so far.
*update*. To date I have lost 60 pounds! My side effects from the 200 mg/ day are non- existent now, but this past Thursday my doc increased my dose to 300 mg. 100mg 3x/day as I do notice I have the urge to drink coming back. I shouldn't rely on this solely for my alcohol issue but it worked so well it seemed nothing else was needed. I anticipate even more weight loss but I will begin working harder myself on my alcohol issues and not just rely on the topamax. *I strongly recommend this for weight loss! I have not even tried to lose weight... I need to but I have just been using it to stay away from the alcohol.
I was put on Topamax back in 2oo8, for 2 reasons, one was the benefits of weight loss and as a usage for mani/depression, for the first 2 months the weight loss was slow a pound here or there but then it started coming off almost a 1/2 pound a day, til I lost 75 pounds in 6 weeks, now I know we are all different, I did regain the weight 7 years later (but that's entirely on me and my really bad eating habits) I am again on Topamax but a really low dosage, which I'll prob increase myself just to experiment (not recommended just something I trust myself able to do) but don't give up hope, half the battle is mental and emotional, try other tricks like writing your goal weight (not the final but for now an obtainable one like a15 pound weight loss) and stick that number on fridge, or find a "skinny" picture of yourself or someone you admire and put it on the fridge or snack cabinet... we can do this!!
I have been on 200mg twice a day since 1/1/2017. I have lost about 15 pounds so far with no effort. However, It has made soda taste terrible so I mainly drink water now. I no longer have ANY desire to drink Alcohol, which I was drinking 1-2 drinks a night..So that probably has a lot to do with the weight loss. The other side effects are tough to deal with. I am extremely tired during the day but have trouble falling asleep at night. My vision has become blurred and if I try to look at things up close, like my grandbaby, my eyes hurt... A lot. I also have the concentration issues and seem to have short term memory loss.
I was prescribed Topamax for Alcohol dependency... It works GREAT for that and for me.. right now it's worth the side effects.
Congrats on the alcohol curbing!!! Are you a smoker? Has Topamax helped?
Thank you! I am not a smoker but I have done some research and found that it helps with smoking also so my daughter is going to talk to her doctor about getting a prescription to so she can stop smoking.
@Beaner63 - I'm a smoker and have been on it for 2.5 years. It had no change to my smoking. If anything, I started smoking more. I did lose 80 lbs though. I've also recently started vaping and have all but quit smoking cigarettes. I only have one occasionally when my husband is feeling lonely smoking by himself.
Hello l was on a lower dose and nothing happened so today l start on 100mg @twice a day l will see l need to loose 28lbs but l am also cutting some of wrong foods out of my diet and trying to walk everyday. I hope this helps good luck to everyone!
I have been on 100mg 2x a day for a few months now and I have lost about 35lbs. I am on it for chronic migraines. I have also modified my diet as well though. Food just tastes different though and I do not eat as much or hardly at all and have to remind myself to eat. It has really helped me lose the weight I needed to.
I have been on 100mg 2x a day for a few months now and I have lost about 35lbs. I am on it for chronic migraines. I have also modified my diet as well though. Food just tastes different though and I do not eat as much or hardly at all and have to remind myself to eat. It has really helped me lose the weight I needed to.
Hello everyone its 3/2/17 l am still on 100mg @ twice a day sodas use to be my best friend now l cant stand them l hardly eat its lunch at the office l would have eaten by now no lunch for me yet l have lost a few lbs but not like some of the post l have read but l am not gonna give up yet! As always good luck
I have been put on 25 mg of this for a tic disorder once a day. It has only been a little over a week and I have lost 5 lbs.
I just started back on it .i had found it a few years ago while trying to find relief from migraines .I went from about 300 to 230 in about 4 to 5 months .but started having episodes of low blood sugar . I would have to make myself eat .What I found great was the fact that food that was good for me tasted ok ..but sweets cokes ice cream were terrible it was so easy to give them up .I craved water fresh fruits veggies ... this time I'm on 25 and not going up as fast or as high .I don't think you need to I think 50 or 75 at night and 25 day would do it .been on it a week i have lost 4 pounds ... fluid... could be but I was on Lasix for months prior to starting back.. I'll try to keep you posted .I know the brain fog and heavy limbs is rough but to lose 15 pounds a month ... more or less i'm so there
It takes 200mg for some folks. I lost 50 lbs in 6 months. It's a big deal considering I'd already lost 120 lbs before that and it was my last bit of weight I needed to get to goal and post menopausal. It took my appetite completely away and struggled to eat anything. It causes malnutrition, hair loss, personality changes with wild mood swings, just to name a few! Oh, did anyone mention it greatly effects your memory and you won't be able to recall nouns? It's a black labeled drug that shouldn't be prescribed off label, but many doctors do! Once you realize it's the devil drug, you have to slowly wean yourself off or risk seizures and all kinds of horrible stuff. Please read through everything you can find online about this drug especially on this forum before you decide to go deeply into it. I still have to wear a wig every time I go out because of bald spots all over the top of my head!
I do not know how long you have been on Topamax but it seems for a while if you are titrated up now. I would say it just is not working for you. I was put on it and had to be titrated down - I am on 50 mg a day 25 and 25 morning and night and have stopped losing weight but my weight loss was immediate. My appetite loss was immediate. I have never regained any weight or appetite. It must not work for everybody.
MollyN, in an earlier post you talked of vision problems. I just wondered if you have been to an optometrist? My neurologist put me on this medication for epilepsy, stressing that it could cause glaucoma and that if I experienced any loss of sight I was to let him know immediately. I would recommend you get a pressure test done on your eyes if you haven't.
Related topics
topamax, side effect, weight, dosage, food
Further information
- Topamax uses and safety info
- Topamax prescribing info & package insert (for Health Professionals)
- Side effects of Topamax (detailed)
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