What time is best to take quetiapine xr thru the day?

Quetiapine is a very good medication.
It's for Anxiety/PTSD Bipolar/Insomnia.
It's been a year now that I started it.
25mg in Am.
400mg at bed. And I have to make sure I take it and get right in to bed because it hits me fast. I have slept everynight since. Had a few issues but solved them quite easily.
1-anything over 100 mg of quetiapine gives me Restless Legs so I take at same time Requip 1 mg and never experience Restless legs.
It also was causing me to dream alot. Not knowing this would help is that I am prescribed 20mg of prozac in AM that caused me drowsiness. So I switched it to nights and it actually stopped the dreams.
I really like quetiapine it has helped me so much.

Hey, I've been taking Seroquel XR for a number of years now, to help me sleep, and I have found it works best for me to take it in the early evening. I take mine at 5:30 pm just after dinner. I find that taking it then it has enough time to start working throughout the evening without overpowering me, so that by the time I am ready for bed, at between 10 and 11 pm, it has taken full effect and I fall asleep easily. It also has enough time to wear off through the night so that when I wake in the morning, usually at 5:30 am, I am fully awake with no hang-over effect.

It takes longer to peak that IR seroquel so I’d always take it about 3 hours before my bed time. The sedation doesn’t entirely improve, you more just get used to it. I’m a little surprised someone would pair the thought of motivation and seroquel. Your mileage will vary but Abilify, Latuda or Geodon would be better options for that kind of thing. If this doesn’t work of course. It can take up to a month to get used to the daytime sedation.

I definitely believe this drug should be taken at bedtime. If you can avoid driving for a day or two, I would. I only took it for one week. It's great for anxiety but I gained about 20 pounds in 1 week. I was advised to stop taking it and was prescribed another drug. I was prescribed a starter dose.