I was prescribed Lamotrigine because after 5 days on 25 mg of Zoloft my anxiety got much worse and after 10 mg (a baby dose) of Nortriptyline for just a week my depression got much worse. I've been diagnosed with GAD which also results in depression. I've felt this way for about 4 months - triggered by very stressful life events. Because I have periods during the day when I feel "normal" and because of my reactions to the Zoloft and Nortriptyline, my pdoc thinks I have a mood disorder - perhaps bipolar 2. I've also had this happen two other times in the past 8 years - also preceded by significant life stressors. The first time it was just depression (although the diagnosis was anxiety) and it passed after a few months without medication. The second time it was mostly anxiety and I took Paxil. I had to wait 8 weeks for the Paxil to kick in but eventually it did and I got better. I was on the Paxil for 10 months. I should note that I've never had a true manic episode. My "ups" are just a feeling of centeredness and contentment - just feel good and normal. My main symptoms are depression and anxiety. Will the Lamotrigine work for me? If so, when should I expect to at least get some signs? It's been 5 days on 25 mg. No bad side effects. Does seem to have helped a little with the anxiety but not the depression yet. Thank you in advance for any replies.
Lamotrgine is an anti- seizure drug that is also used for bi-polar disorder. Your anxiety should keep improving but I don't think it will have any effect on your depression at all. You stated that you had used a low dose of nortryptiline I would speak with your Dr about a drug called doxepin its in the same class of drugs but I think it is a much better drug for depression. I wish you luck in finding some relief. Packard2046
It usually takes a couple of weeks for those side effects to subside when first taking a med like Zoloft, but anyway, you are on a low dose of lamotrigine so you may have to wait until the doctor increases before you notice significant difference. It will help stabilize the mood including depression. It is trial and error ordeal, but worth the journey when you find what works.
Hello and I wish you luck in your care. I am on Lamotrigine however I am on 300mg a day and it is a blessing. I have a lot of issues, but I feel that I would not be here today if it were not for the Lamotrigine! I do still however suffer with depression but it is only because of dealing with untreated intolerable pain. When I was on a pain regiment that worked I felt wonderful. I was happy, had a good quality of life and I loved the results from the Lamotrigine. It did take a while though as the dose had to be increased slowly until I reached the point where it helped me. Be patient I think Lamotrigine is the best medication that I have ever taken and I have tried several, trust me. I wish you luck and I pray that my response has helped. You have to start at a low dose until they find a dose that will help you. I am so glad that I was switched to Lamotrigine. It is absolutely the best medication that I have been on in 30 years! Good Luck, Hang in there!
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