I was on 60mg of Cymbalta and 5 mg of Abilify for major depression for many years. I am a 49 year old female and hated the weight gain from the Abilify. Many years ago I was on Lexapro and it did wonders for my major depression but it pooped out after about 14 months. I was also on Wellbutrin and can't for the life of me remember why I stopped taking it because it, too worked wonders for my major depression. Recently, someone told me about augmenting the Lexapro with the Wellbutrin and the combination is worthwhile. Since I am older and going through hormonal changes, even my gynecologist suggested this change so I spoke to my psychiatrist and we did the change. Its only been a week now as I weaned off the Cymbalta and am going on to the Lexapro on Wellbutrin (both generic). So, I am now on 10mg of Lexapro and 150 mg of Wellbutrin, going up to 300 mg of Wellbutrin. Is anyone else on this combination of Lexapro and Wellbutrin? How long before I should feel the effects of the 2 drugs together? This has been a tough week going through the changes of the drugs and I am going through a very tough time in life watching my mom suffering from a rare degenerative brain disease so that isn't helping my major depression! I just want to know if this combination of Lexapro and Wellbutrin has helped anyone else?? THANK YOU SO MUCH.
I just started Lexapro and Wellbutrin to help for major depression. Anyone else on this combo?
Question posted by RubyRogue on 8 Nov 2016
Last updated on 9 January 2017 by Brittcjacobsen
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4 Answers
Yes I am on both and they are working great. I have bad anxiety and this really does help.
Its a good combo and the Lexapro should work in 2 or 3 weeks and will just kind of creep up on you and the Wellbutrin should work in less than a week despite what people say. The only thing I'd suggest is talking to your Dr about a small dose of Ativan to help with the stress
I take 10ml Lexapro and Lamictal for depression, it works very well. Lamictal is used for epilepsy but it also works as a mood stabilizer. It is as effective as lithium without all the side effects. Talk to your doctor about it.
I've been on both before but not together. I've been on bupropion and Paxil together, actually that's my 1 2 punch for SAD. It works quite well for me. I can actually sleep and concentrate and winter is a breeze (pun intended) for me. The bad is paxil has a way (like all SSRIs) to become a burden after they are no longer needed, so I suggest vigilance and good judgement. Besides the usual side effects all goes very smoothly annually.
Related topics
abilify, cymbalta, lexapro, wellbutrin, depression, weight loss (obesity/overweight), weight, female, major depression disorder
Further information
- Abilify uses and warnings
- Cymbalta uses and warnings
- Lexapro uses and warnings
- Wellbutrin uses and warnings
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