I have been on Lexapro for like 2 years. Last year Dr. added Wellbutrin to help with depression. Since taking this combo along with meds for bp, pregabalin, magnesium. I'm having a weird side effect. Told Dr. about it 7 months ago. I have been talking in my sleep. I can hear the tv, but not quite asleep. Hubby says I'm talking in my sleep. I am acting out the conversation. In this limbo thing I'm reacting to the "dreams". So if someone offers me something I act like it's nothing but I reach for it. My hands act out whole conversation. Most of the time I know what I'm saying but last night and this afternoon nap, hubby says I chatted up a storm.
I have never ever talked in my sleep until Wellbutrin was added to the mix. Very scary. It's like a two way conversation but it's only me.
Side effects of Wellbutrin - Lexapro combo?
Question posted by Missouri Moose on 9 April 2022
Last updated on 13 April 2022 by WildcatVet
Answers
Hi, Missouri Moose!
Boy, this a strange one! It's not an interaction between the two medications according to the Interactions Checker. There is very little mention of it in the literature I could find except for one article which referred to it as a "rare" side effect.
What did your doctor have to say about it?
I would bring it up with them again because this is obviously affecting the quality of your sleep.
You might also think about reporting this side effect to the FDA if you're in the U.S. or a similar agency if you live elsewhere.
If you're in the U.S. here's a a link:
https://www.drugs.com/sfx/wellbutrin-side-effects.html#consumer
Scroll down to the very bottom of the page under Further Information.
Best regards and I hope you can find an answer to this!
Related topics
lexapro, wellbutrin, depression, anxiety, generalized anxiety disorder, neuralgia, pregabalin, major depressive disorder, side effect, magnesium
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