Lamictal & Wellbutrin - anyone else taken this combination and what happened with your weight ?

Hi! I am currently taking Lamictal 50mg a day and Wellbutrin XL 150mg each morning. Both medications have decreased my appetite, so I’ve lost a few pounds. Neither medication is known to cause weight gain. I’ve had more energy and less of an appetite.

I’ve noticed that my mood has more or less stabilized, and I don’t have obsessive negative thoughts nor do I spiral with depression.
I’m hoping it helps improve my ADD symptoms too. (I was diagnosed with depression, bi-polar 2, and ADD). The side effects have been mild-some spotting in between periods (I’m also taking birth control pills), and when I added Wellbutrin, I had very vivid dreams for a couple nights. I noticed some increase in hair loss, but not a tremendous amount.

Has anyone else had irregular periods and hair loss while taking this medication combo?

I've been on Lamictal twice. 5 years ago and just recently. Both times gained 15-20 lbs. I'm not sure about the wellbutrin.

My husband has been on lamictal and Wellbutrin for 2 years and has LOST significant weight. Like a lot. He just has very low appetite since he's been on it. In two years he went from like 290 to 220.

I lost weight, felt more active and my boobs got bigger. On 200mg of lamictal and 10 mg of bupropion. Like almost two cups bigger...

I've been taking effexor, 150 mg. twice daily, and lamictal 200 mg., for about two years. My problem with lamictal is that I feel like I'm on 'pause'! I never want to get off the couch, and I used to keep my house spotless. Now? Forget it! I am not bipolar, but rather in deep depression. I was also diagnosed with ADHD about 15 years ago and have taken adderall, 60 mg., since then. I'm changing psychiatrists soon, and I'm hoping he'll help.

You will not gain weight on these meds! I just started taking Wellbutrin and Lamictal combo about a month ago. I'm taking 100mg of each per day. Some days if I feel I need more, my psychiatrist told me I can take another lamictal and/or another Wellbutrin. I took celexa 40mg per day for 3 years and I think I developed an immunity to it. After my dad passed on November 15th, I needed something better. Celexa made me want to nap all day and was so depressed I couldn't pull myself out of bed. I haven't taken a single nap since I started Wellbutrin and the best part... I've lost 9 pounds in the past month since I started taking it!!! It gives me an energy boost (not a jittery one) and I am so much more productive and I never get hungry until 2 in the afternoon. I take it first thing in the morning and it doesn't even make me sick on an empty stomach. Wellbutrin is a gift from God! Best ever. Hope it works for you as well as it has for me!!!

I am on 200mg of Lamictal, was on 400, it has been an amazing med for me. I was also on wellbutrin at the same time, but no longer on it, due to change in meds, but both together were working well. I am med resistance, therefore, my meds are changed frequently. I wouldn't worry about the weight gain with either or (I too am self conscious of my weight), in fact Wellbutrin (if anything) you could lose weight.

Good luck with your new mix..

Please keep us posted as to how you are doing with the combo.

Kelly

I take 100mg Seroquel 50 Lamictul 450 mg Wellbutrin. Bipolar treatment began 7 years ago.
As far as the question about gaining weight with wellbutrin I can tell you I lost most of my appetite and lost 15 pounds the first month of beginning the drug. I have since gotten my appetite back but only eat half as much as I used to.

12/2014: I'm just adding Wellbutin to 400 mg Lemectil. Hoping for energy and motivation. So thrilled to find this forum. I've been fighting rollicoaster since late 1960s and finally found a great dr this yr. cautiously hopeful.

I am a 22 year old woman who has been diagnosed with depression, anxiety and mood instability. For the past couple months I've been on the same pill regimen- 25 ml of lamictal, 25 ml of zoloft, and 100mg of wellbutrin. I'm a smaller person-5'7"130lbs and I'm sensitive to medicine so this is strong enough for me. Adding the lamictal to everything else has been great! With the wellbutrin and zoloft I felt more normal and upbeat and calm. But when adding the lamictal it helped to keep me at that level nearly everyday. Whereas before I started taking lamictal I would get randomly irritable, moody and spiteful for no reason. I feel like I can finally move on in my life ad finish my degree and hold down a job:) fingers crossed

I took welbutrin went from size 22 to 8 . It wore off and started to take paxil then that wore off. Now on lamictal havent gained 25 mg 2xpday celexa an adivan. Im experiencing joint pain and lechen planus since i started this month. Im small framed too been going thur this bipolar One since1999 been on meds since. Your gonna stay small i went from 2 to 12 on six months from respirdol know how u feel.

Hey I take lamictal 100mg twice a day and and Wellbutrin xl 350mg once a day I either don't have an appetite for a couple a days or have an appetite and still don't gain weight I think it has something in your metabolism

I am on 200 mg Lamictal before bed and 200 mg Wellbutrin twice daily. I have actually had a decrease in weight on this combo. I had been on combination of Serequal, Ativan and Wellbutrin and had significant weight gain. I have lost all of that weight, and then some, since making the switch. The combination works well for me also.
Good Luck!

Since I started on lamotrigine last summer, I've lost about 20 lbs. It's probably because the drug has given me energy I haven't had for over 30 years (and eliminated depression). Instead of sitting in the recliner most of the day, I'm always up doing something.