I struggle with body issues and I'm worried that I will gain weight on this medicine. I was prescribed 50mg 1 a day.
Spironolactone - Did anyone experience weight gain?
Question posted by r1628 on 14 June 2017
Last updated on 17 January 2023 (2 weeks ago) by jdemario25
I didn't put 2 and 2 together until last night because I've been struggling with my weight gain and body changes. I noticed my clothes weren't fitting as well as they used to and I just felt blah and bloated. I am 48 years old and am only 4'8". I'm afraid to weigh myself but I can tell a huge difference. Then while I was trying to sleep, it just dawned on me that maybe it was the Spironolactone? What else could it be?? I'm not eating any different than before and usually after the holidays, I go back to my normal weight but my bras aren't even fitting me anymore. My dr did warn me that my breast would get more tender and get bigger but figured it would be just that! I've only been taking it for maybe about 5 weeks now but wow, what a difference. I know this question is from 2017 - has there been more research on this, I wonder?
HI! I started this medication back in May 2021 for my skin and have been on it till now, recently I have been experiencing stretch marks form on the sides of my thighs over the past few weeks and my body has lost its normal curvature and flat stomach. Personally, till now, I've been pretty skinny and I have a fast metabolism so I've always been around 58KG's, since going on this I haven't changed my usual diet so this occurring on my body has been a very big shock to me, as I would not expect to get stretch marks at my age. I never really had body issues before this medication, again because I was pretty skinny and nothing really affected my weight, but after a few months on this drug, it has really affected my confidence in myself and I do worry if these changes will go away when I discontinue taking this medication. I have been taking 50g 2 times a day (2 pills at night and 2 in the morning).
My acne personally has never been horrible I just get a few bumps and red spots here and there but looking back on photos from before I went on this really nothing much has changed (I've only been on it for 6 months though). It definitely did get rid of the number of pimples that appeared on my face every few days but in the long run, it didn't do that much. But to repeat, my skin has never been cystic or dramatic in the acne sense, so going on it only to experience weight gain and see stretch marks form on my legs at 18 years of age, is not what I needed just to have the perfect skin. After reading these previous reviews I feel the best thing is to go off this medication, especially because the dermatologist I went to did not disclose the possible weight gain I could experience. Again, especially because this medication is not specifically made for the skin. I do not recommend this considering it has been known for weight gain and stretch marks/cellulite. If you want to get rid of your acne that badly, I do recommend asking a doctor to change the medication from this one and look for safer options, especially when suffering from body confidence issues.
Hey there. I’m curious if anyone has successfully lost the weight they have gained from this medication? And what measures did you take to lose it or does your body just naturally go back to normal eventually? I started taking this med Jan 2020 and stopped Oct 2020 due the the 10-15lb weight gain in that short amount of time. I’ve NEVER had curves and now my booty, thighs, hips, stomach feel huge. It’s so uncomfortable and feels like I’m walking around with 2 gallons of water in my legs. Nothing fits. I’ve been off almost 10 months and not a single pound has been lost. Why is this? It should be out of my system by now and my hormones should be going back to where they were, yeah? I have not broken out on my face since stopping, but have developed back acne which was never a issue prior. So I do believe my hormones are all jacked up...
RE: Weight Gain
My story is very similar to everyone else that wrote a review. I've worked by butt off to lose weight for 5+ years and have succeeded.. until this medication. I assume its from it because everything else in my diet, and exercise regime is the same, I've even kicked it up a notch. Around 5lbs gained, while taking a few months, which isn't too bad, however I'am short and any lb makes a difference, but it better come off. I quit taking this med recently after wondering if this was causing the weight gain, it took a month to help clear up my skin, (which I still was breaking out while taking it just not as bad) I felt like it was not helping my blood pressure either, if anything it was a little higher.
I have noticed my bottom feels thicker from the inside out & my hips seem wider, and my stomach which had abs, now has more of a significant lower belly pooch, and my legs seem bigger, my pants are tighter in areas, I am very upset as I have worked SO hard to keep the weight from coming back on, just to have some pill ruin that for me in a matter of a couple months! I just feel defeated at this point. I don't want to be a negative attitude here just frustrated.. We will Overcome this!!!
Hi, I am experiencing exactly the same symptom with many shared here. I started to take Sprio 100mg a day for my severe hormonal acne mainly around my jaw line. I went to see a new cosmetic dermatologist and she prescribed it for me (not a regular derm I go to). I went to see her to get some kind of topical cream or laser treatment and so I was reluctant to start spiro when she prescribed it. But she assured me she even takes it and has no side effect (she looks like a porcelain doll, perfect skin and slim).
It worked great and for someone who has been struggling with acne for the entire my life (I'm 44), it was a miracle pill and I was so happy about it. She told me to take this until absolutely no acne, then I can stop. My skin cleared up in 4-5 weeks maybe 90% and I was still getting some under the jaw line. So I kept using it. I started in Dec 2019. But around March or so, my period became more frequent and I felt my jeans are tight. But I was thinking that's because I could not go to lap swim as frequent as I do so it was the cause. I was eating exactly the same.
But things got really crazy in May or so. Now my period came in every two weeks and I was really really tired all the time, and before the period, I could not even stay upright and had to lie down because I was dizzy. I started doubting it must be spiro because I am not taking any other medication and no lifestyle change. Then I recalled my muscle felt a bit weird after I started taking it too. I don't weigh regularly so I could not tell how my weight gain started but I gained almost 8 lbs and it started rapidly around since April. And exactly the same area other people mentioned here. Mainly stomach, thigh and breast (I usually have no breast, and only time I feel this way is before period but not this much. I felt my breast tender everyday... since Spiro).
And it is more of a solid mass of layer than flabby fat. I almost believed they were new growing muscle as I started high-intensity exercise at home as we cannot go to gym anymore due to covid. I was so conscious about my weight and it seemed the best exercise I can do at home. But it was just a very thick chuky type of fat : ( It's so depressing and I can't fit any of my jeans, only some baggy ones I have.
After I realized it is spiro, I stopped taking it at once because it was more mentally daunting for me to keep on taking it for gradual termination of drug while knowing I am consuming something that is actively causing this horrendous weight gain every minute.
It's been almost 4 weeks since I stooped taking it and my weight maybe went down 1 or 2lbs. It's more of how I am bloated and retaining water that day. I'm trying to get some supplement for water retention now. So I don't think I lost actual fat.
Good news is that I haven't got any massive hormonal acne. But I got countless tiny skin-color bumps mainly around my jaw and forehead, face line, right after I stopped. Almost felt like all my pore were clogged. I thought it is some type of allergic reaction because I had a very similar allergic reaction before so I went to see my regular derm and he said this is hormonal breakout and prescribed me tretinoine 0.05 cream. Fortunately they are not that visible unless I check my face with certain angle with light. When I feel with my hand I feel so worried but when I check them in the mirror, it is not noticeable. So I am trying hard not to think about them during the day. Plus, because of facial masking , I am able to stay less conscious about it. Now week 4 with tretinoine cream, I see some of my bumps were cleared out (promising sign!).
Referring to other ladies' info, I'm not sure I can return to my normal weight right away, hopefully in two months or so, otherwise I am thinking to get some hormonal therapy.
Everyday I feel so depressed when I decide what to wear because I can only wear a certain outfit. But I am more angry and ready to kick out this unwelcomed tenant from my body! (Trying to use this great amount of sadness and anger as a fuel of my exercise, can't think of any other better way to release this unwanted feeling.)
I didn't see anyone mentioned they had a similar breakout like me after spiro (micro bumps all over my face line), so I wanted to share my story. Cause I am pretty sure many are very worried about the relapse after stopping sprio. Instead of big cystic acne, it could purge like mine.
I really wish everyone that we all reverse this unwanted side effect together! Let's not give up~
Don’t take this drug. I was on it for almost two months and gained 10 pounds. I went off when I realized it. I have not been able to lose the weight since stopping. I have never had a problem losing weight and now I can’t. It also has completely changed my body. My hips are much wider. It is mind boggling how I can eat right and exercise and still not lose a pound.
This July I was prescribed spiro for hair loss and I took it for about 25 days, then immediately stopped it because I gained 10lb. I also experienced heart palpitations, HAIR LOSS and acne came back! ( I have been on birth control for 5 years with clear skin, no weight gain)
My dermatologist didn't believe it was the spiro doing all this but I was like F*** this I'm done with the med. My blood tests showed my hormones were good before taking the spiro, so really everything pointed that the med did all this.
I am about a month off the med and still haven't lost the extra 5 lb, but heart palpitations stopped, hair got better and face cleared back to normal.
I will keep exercising like I always do and eat clean, and I believe my hormones will stabilize after stopping this weird-ass med...
Ladies, I took spironolactone about 4 years ago for only two months and the damage was extensive. I was prescribed a low dose of 50mg to clear up my cystic acne, but it was never mentioned that it could potentially cause damage to my thyroid or cause estrogen dominance. I was 5'6" and 130lbs. and lifted weights four times a week - I was very fit and ate well (organic, whole-foods). Two weeks into the meds, I noticed I wasn't fitting into my clothes, everything was tight. Bottomline - I gained 15 - 20lbs in two months and my cystic acne got worse, I took myself off the meds immediately. After some trips to the doctor - derm and gyno, they said my thyroid was low, but they were afraid to give me anything due to my last reaction. I started taking a zinc supplement and I lost about five lbs over 4-6 months. Also, this lovely med caused my skin to become so sensitive that I now have melasma on my face.
No matter what I did I couldn't lose the weight! *** Just in the last 60-90 days I have started intermittent fasting only 13 - 16 hours a day and I have now started to see massive improvements. If only I had found out about it sooner. All the docs could offer me was synthetic hormones or thyroid meds, but I was terrified to take them. But FASTING has nearly cured me and staying away from soy cured my cystic acne for good. I felt I had to post this considering I've tried everything else (supplements and exercise). Hope this helps someone!!
I’ve been taking this medication for 2 months. Thank god for this post. my doctors assured me it wouldn’t make me gain weight but it definitely has! I’ve never had my stomach bulge out like this before. Not taking it anymore.
I was on Spiro for 2.5 years for hormonal acne and hairloss. I gained 20 lbs in my stomach, boobs, hips, and thighs. I have never seen so much cellulite on my legs in my life. I've been off of it for about a month and I'm RAPIDLY losing the weight. I'd avoid it at all costs. Yes, it clears your skin but it's not worth the cellulite, stretch marks, and deflated boobs. Find a topical antiandrogen if you're having hormonal acne.
Spironolactone is normally taken at the dose you are using for high blood pressure and fluid control and for those with heart conditions. It helps remove excess bodily fluid. It helps with acne but that is not what it was designed for. It removes fluid in a different matter and mainly for those who reject the other forms of a diuretic. What are your health problems as to why you listed prescriptions?
Do not take Spironolactone! Sure it is a God send when it comes to clearing acne because it does work, but you are most likely going to gain weight. I started Spironolactone 25mg then increased to 50mg daily. I began therapy in March and yesterday when I had my physical by PCP I had gained 24 pounds!! She knew right away that it was the Spironolactone due to the effects on the hormone levels. Dermatologist was confident that it wouldn't cause weight gain when I was started on it, but they were wrong! They really need to be more informed about it.
I absolutely loved the results from it, but It is definitely not worth the weight gain! I was doing nothing different the whole time of treatment. Continued to exercise 6 days a week and counted my calories strictly. I finally put 2+2 together and my PCP confirmed it for me. My body is totally different now with bigger stomach, thighs, and butt. Cellulite like you wouldn't believe. It's horrible! I should've stopped it sooner, but I was so happy with my skin after years of hating it. I'm not looking forward to the acne that will probably recur, but I would rather deal with that and try something else than to be fat!
- Spironolactone uses and safety info
- Spironolactone information for Healthcare Professionals (includes dosage details)
- Side effects of Spironolactone (detailed)
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