Sertraline - Anyone seen tremendious weight gain ?

I’ve been on sertraline for a year now,50mg a day and I’ve gone from 9st to 11 and half stone. Nothing I do shifts the weight, I go to the gym 4 times a week my diet is the same and the weight just plies on.

I have been taking sertraline 150mg for 3 years and gained over 4 stone despite going to the gym 4-5 times a week for high intensity workouts. I literally couldn’t loose anything during my time going to the gym which I did for almost 2 years.
I ended up having a gastric balloon and lost this weight over a 10month period but I did suffer with nausea and vomiting a lot. I regained 3 stone in less than 2months which seems drastic and I am not exactly stuffing my face either! Even tried very low Calorie intake and I couldn’t shift a 1lb. I’m definitely going to speak to my GP to see if I can switch medication.
I have never had any issues with weight prior to this and rarely fluctuated more than 3-4lbs for the last 20 years plus. I’m by no means blaming the medication but I was just wondering if sertraline effects weight on such a drastic scale??

Alge2060,
Did you manage to get off of sertraline? I've been on 75mg for 4 months. I've put on at least 10lbs since starting sertraline. I've been questioning if I should go back down to 50mg in hopes that I may loose some weight. I also have low sodium. It should help that as well. I too have no energy or motivation to do anything. Which is depressing in itself. I love how this drug is working for me otherwise.

Kind of a late answer but I was on sertraline for a year and a half. I gradually worked up to 150 MG's. In that year and a half I have went from 110 lbs to 190. I'm now coming off of it due to weight gain and I am down to 25mg and have already lost 5 lbs.

I was on Zoloft for 10+years. I gained a tremendous amount of weight even though I work out vigorously 4x a week. I eat normally and just kept gaining weight. I’ve been off for about 2 months. It has been very difficult with the withdrawal but I’m losing weight. I haven’t changed anything about my workouts or diet.

I believe that Zoloft has a mechanism that messes with your metabolism to a point that makes it impossible to not gain weight. At the same time it makes you overeat. I got to the point where I felt like it wasn’t helping my mood anymore and the weight gain was very bothersome. I don’t believe they are honest in regards to the effects the drug has on weight gain.

For anyone that experienced weight gain while taking Zoloft. How long after you stopped taking it did you start losing the weight?

absolutely it causes huge weight gain especially for me i use to weigh around 10-11 stone now i weigh 16st i eat less than 1800calories a day drink 3 beers a day and the weight just increases i wish id never bothered taking them but im stuck on them now however i am starting to reduce now to see if i loose weight ...

This happened to me. I was at 113 when I started. My weight now is 160. Maybe there’s another antidepressant that works the same without the weight gain?! : / prayers to you as you work through this. The struggle is real

I have been on Sertraline for about 3 yrs now for anxiety and depression. I started at 50 mg daily for about a year. Then my doctor increased the dosage to 100 mg daily. Since the dosage increase, I have put on about 50 lbs. I become out of breath just bending over to tie my shoes or just walking up one flight of stairs. Just everyday routine things leave me gasping for air. My husband was on 100mg daily and had the same issues. He abruptly went off of it and lost the weight fairly easily. I'm just scared to try a different drug because mentally, Sertraline is working for me but I absolutely hate the added weight. This is the only site that has confirmed my suspicions. Every other site has showed zero correlation between Sertraline and weight gain.

I, like you, found sertraline suited me. I'd lost my father, and it lifted my spirits , made me more calm. I took this daily for at least 6 months, even at the lowest dose of 25mg (I am sensitive to drugs). Then the weight crept slowly up. All my life I have been slim and I find I am not used to carrying round this extra weight - almost a stone. Nothing fits. My stomach in particular is gross, and my thighs lumpy.
I am not eating more, however, because I can't - I have an ongoing stomach complaint which I am being investigated for so it isn't that I've been overeating. I have decided I shall come off Sertraline, albeit slowly and wait for the weight to drop back off. I guess I could have been taking it too long, maybe?

Hey! So I was on SSRI's for 7 months. Initially, I was incredibly spaced out for the first 3 weeks and as a result, lost a lot of weight - to the point where people questioned if a previous eating disorder had come back. After things had settled, I had gained this weight back and arguably more than I wanted to. However I wouldn't blame the drug... I was more at peace internally and in a better frame of mind, thus felt okay when approaching food whereas previously, my levels of anxt coupled with determination suppressed feelings of hunger. I did have occasional night time awakenings whilst on this drug, which probably made me crave sugary foods more. With that said, it's not something that can't be beaten with willpower and determination. Hope you're okay and that this works/is working for you and anyone else out there taking it.

I've actually been forced recently to stop taking this medication because of some insurance issues. I began taking it after I had my daughter about 8 months ago. I had thought my weight gain was still just leftover from my pregnancy.. but I had done anything and everything to try and control it. As soon as I stopped taking the medication, my body is now feeling like itself again. Not only am I coming down to my normal weight, I've also gotten my sense of libido back.. which was completely nonexistent on the medication. Once my insurance is active again, I'm not so sure I'm going to continue taking it. Decisions decisions

I never had a weight problem, then I got on sertraline 50mg and gained 20 lbs. The med works so well but the weight gain is very uncomfortable!

@Nicole. Hi! Have you tried one of the more weight neutral antidepressants like Wellbutrin or Trintellix? Everyone reacts differently to every medication but gaining weight on one doesn't mean you'll gain weight on another.
BTW, diet and exercise have little to do with weight gain... these medications change your metabolism... in fact, almost ALL psychotropic drugs have this propensity. You can control how MUCH you gain to a degree but if you're sensitive to the drug some weight gain is inevitable.
Wellbutrin: Very common (10% or more): Weight loss greater than 2.3 kg (up to 28%)
Trintellix: Common (1% to 10%): Decreased appetite/weight loss