Aside from crippling depression and anxiety, and restlessness and irritability, and unable to derive pleasure from anything, and no energy, and unable to get myself to function and do simple tasks, aside from this crippling depression, I also suffer from Crohn's disease and colitis, but predominately Crohn's, and I have all features ( from my mouth to my anus) and depression and my nerves manifests Crohn's. And medicines are unbearable w the side effects or worsens my depression and anxiety ( just takes on a whole new form of itself ) and I have had chronic depression since I was 14, and going on 49. I have missed out on over 35 of living. It’s torture!!!