You could read details on: https://www.drugs.com/interactions-check.php?drug_list=1115-648,440-203, besides other side effects of the meds which would be listed on: for Prozac: https://www.drugs.com/prozac.html and for Wellbutrin: https://www.drugs.com/wellbutrin.html
Take care, best wishes!
Taken at the right dosages, Wellbutrin with Prozac is a great combination for depression and anxiety. Don't let the possible interaction scare you. This is extremely rare. Weight gain is also unlikely particulary with Wellbutrin. As long as you watch your calories consumed are less than or equal to calories burned, you'll not gain weight. Side effects when first starting the Wellbutrin may include some headache and jitteriness, but this will go away in a short time.
I take trazodone and wellbutrin. The wellbutrin actually gives me energy and increases my metabolism. I've lost weight since being on it which is great for my depression and considering when I was on Lyrica I gained 50lbs. Remember as already stated they list side effects but some of them are so rare. The worst I had was sweating when I was first on it now I don't even have it. Depression wise I can honestly say in 6yrs of having it and being in dark gloom from Nov-feb and getting severe in winter this is the BEST I have ever felt.
I take wellbutrin & celexa. I never tried prozac, but I knew a old friend of mine who took prozac & she gained weight off of it. But the wellbutrin taken with the prozac might eliminate that weight gain effect altogether. I find that the wellbutrin has helped eliminate my crazy cravings for carbs, sweets & sodium rich foods. I also noticed that when I took zoloft that it packed on the pounds, where as the celexa combined with the wellbutrin didn't. If you eat healthy while taking these antidepressants, I believe that you will not gain any weight. Good luck 2 u!
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