I have had two Prolia injections and am scheduled for another one in October. My main side affects are aching muscles, primarily in my hips, mainly at night while sleeping and walking during the day . A 2013 Dexa Scan revealed that I was at a -4. My doctor said that she had never seen a number that low and that I was at risk for compression fractures. It showed that I had osteoporosis in the neck and spine. I have never had any broken bones or fractures and am otherwise very healthy. I am 61 years old and exercise at Curves and do Yoga on a regular basis. Have studies been concluded on Prolia and show it to be more effective than Fosomax or Boniva? I would like some more research before I have my next injection.
Yes, you should get a bone density test to see your progress which should show up by now. My progress showed up just 7 months later after just one injection, but with no other injections my very intense side effects have lasted almost 3 years.
Yes, the research shows that many women do show bone increases. BUT, the drug slows the bone-breakdown process -- but also slows the entire bone-remodeling process. Which means that the bone density is different from normal bone building. Over the long term, it's not yet clear what this will mean. Doctors are warned to be on the lookout for osteonecrosis of the jaw, atypical fractures, and delayed fracture healing in patients taking Prolia.
Another possible downside to Prolia is that its target, the RANK ligand, plays several roles in the immune system. In clinical trials, women taking Prolia had a higher risk of serious infections leading to hospitalization, including heart infections. Skin reactions such as dermatitis, rashes, and eczema also were reported.
The most common side effects of Prolia® include back pain, pain in the arms and legs, high cholesterol, muscle pain, and bladder infections. Possible serious side effects of Prolia® include serious allergic reactions, low blood calcium, severe jaw bone problems, unusual thigh bone fractures, serious infections, skin problems, and bone, joint or muscle pain.
Good luck and would be interested in what you decide to do and what progress you have made.
- Prolia Information for Consumers
- Prolia Information for Healthcare Professionals (includes dosage details)
- Side Effects of Prolia (detailed)
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