Premenstrual Dysphoric Disorder - I am taking 150 mg of Wellbutrin XL for mild depression, anxiety?

Hi, this response is coming late but hoping you are doing ok. I was treated with Zoloft for PMDD, but due to SSEs my doctor switched me to Welbutrin. I've been taking 150mg and it's doing great. It's about the time of month when my episodes start and I felt them coming on but handled it much better. My dose probably needs to be increased so that the episodes don't come at all, so I'll be speaking with my doctor about it. Hope this helps you.

I know this is an old post, but I wanted to share my experience. I also have pmdd and I am 38 years old. My Obgyn prescribed Wellbutrin about two years ago. I started out on 100mg twice a day then after a year I called and had them to increase my mg to 150mg twice a day. This medication has done wonders for my hormones and my periods. I hope that you found relief with yours

35girl I know this post is old but am very curious if you found relief. I'm a 38 yr old woman for the last year my PMS has gotten severe. I no longer feel like myself, I'm crampy, irritable and emotional for about 2/3 of my 23 day cycles!!

I already take Wellbutrin XL 150 mg once a day for mild depression. Now I feel like I'm back at square 1 and it starts about 10 days after I start my period. I was thinking of getting the dose raised to 300mg a day as an alternative to the Zoloft/Paxil that my Dr was mentioning a few months back.

Hope you have found relief!

Great answer echo. My daughterinlaw (ex)also suffered thru this disorder & tried everything in the world! She even had my son in therapy to deal with her bad, horrible moods over this. After many years of suffering, her doctor decided she needed a hysterectomy (not sure it they left the ovaries, but probably) Anyway she had the two children she wanted, so it was not a problem for her to do this, & WALLA! No more problems what so ever. She was still a bitch (inborn), & divorced my son who now has custody of the two kids because she just couldn't deal with it, but the menstral disorders are gone forever. No more depression all month long that was always worse before & after her period. Now this is an extreme solution, but if you have to go that far, it will help you I am sure. Hope this gives you something to think about. I know how bad she was, & it helped her extrememly...

My first thought was start writing ur congressional reps about the huge disparity in R&D money for men vs women! But since might take awhile... my ob/gyn prescibes Elavil, an old school antidepressent that has several off label uses (migraines, pain, insomnia, etc.) & it really seems 2 help at a very low dose. He's also prescribed Soma which I take w/ either Rx naproxen or Rx ibuprofen. I also get 10 5mg Norco & 5 10mg Valium (the valium works 4 sleep & is also like a muscle relaxer 4 cramps). This doesn't make my month peachy keen but it's the best I've felt in the past 2 yrs. He's talked about something like Xanax but I haven't decided if I want 2 do that. I'm sorry u have 2 suffer from PMDD too. Here's hoping 4 some better research & solutions that don't invole hormone. Just started yesterday & have been up 3 hrs with my heating pad, peppermint tea, & a box of kleenex :-(