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Prednisone - How fast does prednisone work on gout?

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suzanne66 19 Jun 2017

Gout is a painful form of arthritis that typically attacks the big toe. Other joints affected include foot, ankle, knee, hand and elbow joints. The onset of gout is usually sudden, causing intense pain, redness and inflammation from the build up of urate crystals within the joint. Prednisone is used to treat an acute attack of gout by helping to reduce pain and inflammation. The earlier prednisone is given in an attack the more quickly the attack can be controlled. The starting dose is usually around 30 to 50mg once daily or in divided doses until the flare begins to subside and then the dose is tapered down, usually after 7 to 10 days.
https://www.drugs.com/health-guide/gout.html

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dquinn39 13 Jan 2021

I can only speak from my experience so bear that in mind. I had my first attack roughly 8 to 10 years ago. I have had progressively more attacks or 'flare-ups' over the past few years, now being 68 in January 2021. I have recently found that Prednisone does reverse my attacks without requiring Colchicine or Allopurinol. I have the 21 4mg tablet pack and find that if I catch the attack in the first 6 to 15 hours, the swelling and pain are gone in less than 24 hours and depending on the severity, full-reversal has occurred in less than 12 hours. I probably have mostly mild attacks but the last untreated attack I had last April 2020 took more than 5 weeks to resolve with no treatment. During the early stage of an attack I notice a slight localized swelling/pressure pain progressing over the first twelve hours, seeming to drop in intensity the second day on occasion and full pain with swelling occurring the later the second to fifth days without treatment. Taking 4 to 8 mg of Prednisone twice, roughly twelve hours apart in the first 24 hours, that stops the attack and I'm back to normal: no cane, Ibuprofen, or Ace bandage resolving in the next 8 to 16 hours. This is my experience and may not be the same for others. Once the pain and swelling are gone I stop taking the Prednisone as I do not like to over-medicate and there does not seem to be a beneficial relation with recurrence and length of dosing. Also, I have been unable to correlate gout attacks with specific trigger foods/diet. My attacks have occurred on days where I have had cherries, fresh, dried, or juice and not on days where I've eaten red meats or seafood. Two recent attacks have occurred in coincidental relation to consuming a small glass (less than 4 oz.) of red wine and the other white sparkling wine both within 8 hours. Everyone is different. I don't drink often and this is not meant to be anything other than anecdotal since I have had wine on other occasions with no attacks.

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