I have tried many, some work very differently. I heard some generic's are 20% more potent than Brand Name Xanax and some are 20% lower in potency. Does anyone know which ones are which?
What is the most potent or effective manufacture of Alprazolam?
Question posted by sinistermonk on 10 March 2013
Last updated on 28 February 2022
I have had Greenstone Lab
Dava which was Stada on my bottle,
I am on 4-7mg alprazaolam a day and my tolerance cant handle the changes in manufactures, they shouldn't be aloud to lower potency that much between generics.
Actavis is the only one that works for me re: potency. Also, the "fillers" used in generics can be a factor as per my pharmacist.
The active ingredient is FDA regulated- the fillers, coloring and other ingredients are not. The efficacy of the pill can differ wildly I’ve heard Greenstone is the best, but most pharmacies aren’t stocking it.
"A generic medicine works in the same way and provides the same clinical benefit as its brand-name version. This standard applies to all FDA-approved generic medicines. A generic medicine is the same as a brand-name medicine in dosage, safety, effectiveness, strength, stability, and quality, as well as in the way it is taken and should be used.
The FDA Generic Drugs Program conducts a rigorous review to make sure generic medicines meet these requirements.
In addition, FDA conducts 3,500 inspections of manufacturing plants a year, ensuring compliance with the agency's regulations on good manufacturing practices.
FDA staff also continually monitor drug products to make certain the medicines at all levels of the supply chain, from active pharmaceutical ingredients (API) to products being sold to consumers, are safe, effective, and high quality.
FDA requires drug companies to demonstrate that the generic medicine can be effectively substituted and provide the same clinical benefit as the brand-name medicine that it copies. The abbreviated new drug application (ANDA) submitted by drug companies must show the generic medicine is the same as the brand-name version in the following ways:
The active ingredient in the generic medicine is the same as in the brand-name drug/innovator drug.
The generic medicine has the same strength, use indications, form (such as a tablet or an injectable), and route of administration (such as oral or topical).
The inactive ingredients of the generic medicine are acceptable.
The generic medicine is manufactured under the same strict standards as the brand-name medicine.
The container in which the medicine will be shipped and sold is appropriate, and the label is the same as the brand-name medicine's label."
Key words: FDA APPROVED
You are absolutely correct, I don't care what anyone says different pharmaceutical companies vary in strength some are worthless! And it should be against the law for them to switch and change and not tell you. Eespecially when one pharmaceutical company buys out another and gives you the same week medication that you have requested NOT TO BE GIVEN... ( And you are told it is not the same pharmaceutical company therefore cannot be the same medication! )You can ask your pharmacist to put in your chart what you will and will not accept. If they give you the song and dance we only get in what they send us look for another Pharmacy. I find Greenstone and Activist to be the best. I hope this helps I know exactly how you feel.
When it comes to the best generic Xanax, alprazolam, you want to get the Greenstone generic brand. The company that makes Xanax, Pfizer, owns Greenstone so they’re made by the same manufacturer. It is the closest to the brand name you can get. My Dr. always specifies this exact generic brand only when he writes my Rx. I have tried other generic brands in the past and the Greenstone brand definitely works better, and it is not just in my head. I suffer from PTSD as well as a major anxiety disorder. So it’s not a psychological thing. It honestly works better! A lot of people think that all generic medications are the same as the brand name but that’s not always true. My doctor was a pharmacist BEFORE he became a doctor... So I trust he knows what he is talking about.
I've always taken the generic, alprazolam white 2mg bars enscribed GG 249. And weirdly thats my preference. But today I got the brand name Xanax white 2mg bars enscribed xanax and 2 on the other side. But they seem so different, and I dont like the differences, they taste different for one, and they are very hard to break in half let alone crush. And honestly at first I thought they were fake. They seem weaker to me, and maybe idk its because of the way I take them I crush them and need a straw and dont take them orally if you know what I mean.
Can anyone tell me why they are not having the satifying effect I used to get with the generic brand?
When you talk of 20% difference in a 1mg pill, it is such a minute amount, your body will never know the difference. 20% of a 10mg pill is only 2 mg. Your body wont be able to detect that difference. Your mind, however, can do funny things.
May I ask where you heard/read that different manufacturers are less or more effective than the name brand?
It's usually a matter of opinion on which manufacturers work better or not.
I've found that all the generics of Xanax, (that I've tried, and I've tried many) are usually equally as effective.
You could call different pharmacies to find out which one carries the brand you prefer. Or ask your pharmacy to order the one you prefer.
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