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What is the mechanism of action of Bupropion?

Responses (1)

WildcatVet 1 Feb 2013

Hi, CdayCS!
Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine and dopamine, and does not inhibit monoamine oxidase or the re-uptake of serotonin. While the mechanism of action of bupropion, as with other antidepressants, is unknown, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.

This was copied from FDA Prescribing Information. Best wishes, WC

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