What is the mechanism of action of Bupropion?
Question posted by CDayCS on 1 Feb 2013
Last updated on 18 May 2021
Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine and dopamine, and does not inhibit monoamine oxidase or the re-uptake of serotonin. While the mechanism of action of bupropion, as with other antidepressants, is unknown, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.
This was copied from FDA Prescribing Information. Best wishes,
- Bupropion uses and safety info
- Bupropion information for Healthcare Professionals (includes dosage details)
- Side effects of Bupropion (detailed)
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