Ok i have Gad and depression and currently taking 60 mg a day for it,but it tends to wear off about 2-3 pm i take it daily @ 8 am is this normal? Should i tell my dr? What do you take for depression? Does it help?
The maximum recommended dosage for Cymbalta is 120mg/day. I have taken it with good results. Once you have been on it for awhile it should stay at a pretty steady level in your blood so not sure why the let down. I would discuss with doctor definitely. I now take Pristiq and Wellbutrin with excellent results, but we are all different.
Cymbalta has a half life of 12 hours so unless you have an extremely high metabolic rate it should not be wearing off in 6 or 7 hours.
I was on Cymbalta for chronic pain and it actually caused depression and anxiety for me. I took mine at 9am and after 4 weeks being on it by 3pm I would feel very down to the point that I was crying. That can be a side effect of SNRI's and SSRI's mostly in those 25 and under but I am 51 and it happened to me anyway. I actually know a number of people who had the same problem with it.
Something you should talk to your doctor about.
- Cymbalta Information for Consumers
- Cymbalta Information for Healthcare Professionals (includes dosage details)
- Side Effects of Cymbalta (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Updated 6 days ago • 196 answers
Updated 15 Nov 2014 • 1 answer
Updated 3 Jan 2017 • 2 answers
Updated 14 days ago • 13 answers
Updated 9 Feb 2018 • 10 answers