Hello there. I gained 70 pounds in one year on Abilify. I went from being 5’3” at 110 to 180. This is causing me great depression looking at myself in the mirror and not being able to fit in any of my clothes. I recently stopped taking Abilify. Has anyone had any success with losing weight after stopping the medication?
Will I lose weight after stopping Abilify?
Question posted by Adamsmom2010 on 18 Jan 2018
Last updated on 19 December 2022 by DonnaAM
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13 Answers
I gained 40lbs on Abilify. I currently am taking 20mg down from 25mg I will be knocking off 5mg every 2 to 3 weeks. I will lose all the weight I gained I am sure of it cause the last time I quit Abilify I lost it all with out trying. Good luck to you. Don’t quit cold turkey it’s absolutely terrible.
I am currently on my third time taking Abilify, but have tried other anti-psychotics over the past twelve years since a car accident gave me a head injury and PTSD with psychotic symptoms. I am 34, and I noticed gaining a lot more weight than when I took Abilify at 24 and thirty. I am 5’7 and my regular weight is 130. When I first started Abilify I got up to 150. I took it for two months. The weight completely came off without trying at that age once I stopped. When I was in my late 20s and tried Abilify again I was on it for a couple of months and got up to 160. I don’t remember if the Abilify made me binge eat and time
by around age 30. Now I have been on Abilify for four months and I’m 190 pounds. My dose has been 10mg. I’m cutting back to 5 mg. I’m tapering off because while it helps me with depression it really just numbs me to the world, and I have no social life anymore outside of church, no dates, because I am so depressed and insecure about my body being so heavyweight. I know we ought to embrace our healthy minds and bodies but Abilify could not be good for the heart with its rapid weight gain side effect and almost everyone in this forum has noted depression along with weight gain so there is a catch 22, taking Abilify to cure mental illness will probably make you mental and distort your body. What I have found about the weight loss and gain is our metabolism slows as we get older and depending on what we consume in conjunction with the Abilify, it can be controlled only a little bit, and as I grew older I gained more weight with the medication. I hope it all comes off again when I quit or switch to Latuda which I have taken before, is comparable and does work, or Effexor as someone else here recommended. Good luck mom and all other Abilify patients!
I realize this is an old question but for anyone still looking for an answer, it's been 3 months of being off of Abilify and I have not lost any weight at all! It helped my anxiety/irritability but I put on 15 pounds in a little over a month without changing any of my habits. I'm really struggling mentally because of it.
I too am afraid I am stuck with my massive weight gain from Abilify. I have been on Abilify for about 9 years. 2mgs a day. Not only have I gained about 70 lbs but my breast size doubled in the first couple of years. I used to be a B cup and very thin. Now I am a D cup and have a huge belly. I went off Abilify for about 3 months and didn't notice a budge in the weight. My depression got so bad again and I went back on because Abilify works for me. It seems the weight is impossible to lose though!
I started out at 5’3” 125 now I’m 170 lbs. like you I am very depressed. Gonna stop my meds
Hi, Trina!
If you do stop them do it with a tapering dose schedule supplied by your doctor. Cold turkey or trying to stop on your own will probably lead to you having withdrawals... which are no fun at all!
Best regards,
I gained 60 lbs on abilify. I've been taking it for 4 years. I am weaning off of a 5 mg daily dose and still taking 2 mg daily. I have lost 16 lbs in 3 weeks! My hgba1c is also elevated for the first time in my life since starting abilify. So, hopefully that will come down too. So, yes, I would say you will lose weight after reducing or stopping abilify. Good luck!
I took Abilify for over 5 years. My weight became a constant rollercoaster. Gaining then losing the same 50 pounds several times. I struggle with Anorexia, so this was a nightmare for me. I became severely anorexic three times, losing too much weight, (the losing weight was extremely difficult though) all while trying to control my overeating, intense food cravings, and abnormally fast weight gain I experienced. I personally believe abilify should never be prescribed to someone with an eating disorder. They very real side effect of weight gain is too disturbing. I have stopped taking it for 2 weeks now and hope my weight will finally stabilize. I am on venlafaxine, and Wellbutrin now.
I have been on it for 3 years and have had 27 pounds slowly creep up on me. I spoke to my provider this morning and am going to taper off. I weigh more now than when I was pregnant.. I have not been able to lose with diet and exercise so I am hopeful.
I have had the exact same experience as you. You may not reply as I realise this was written a while ago but taking abilify when you've had anorexia is highly distressing. I wonder whether you weight ever went back to normal, im 6 weeks off abilify and haven't shifted any weight after gaining two stone on the drugs it is highly upsetting and distressing
Hi Beth! I have been off Abilify for 2 years now. I did not lose any weight by stopping the medication. I eventually switched to Effexor which has had absolutely no side effects for me and have been on that since. I had to work my butt off to lose the weight from taking the Abilify by doing strict keto. I am still working on losing all the weight I gained, but I am down a significant amount. I wish the best for you!
Hi adamsmom2010.
Thank you for your reply. This is highly distressing for me to hear and no surprise. The drugs have significantly effected my metabolism which is now very slow. I am worried the weight will never come off. I eat very little and am vegan anyway. I over exercise and I fear it will never go away now that I have taken the abilify. I can fit no clothes on and feel massive. The doctors have no idea how psychologically damaging this is to someone whose had an eating disorder most of their life. Did you finally manage to shift the weight then? I can't help but feel it will never come off and its every so distressing for me. Thank you for your help
I had problems with Zoloft! I gained more weight with Zoloft than the meds that I'm on right now! I'm losing weight with Abilify now. I'm hoping that the increase won't affect my weight as I'm on a soft foods diet due to that I don't have teeth anymore. I'm hoping that the 5mgs of Abilify won't make gain weight because I take it at night for my sleep and my impulsiveness.
I don’t know I would get off of Abilify myself, I also gained 70 lbs and don’t
Know how to bring it up to my Dr her answer is WW
Hi Linda 1695! Just a little update since I posted this question in early 2018. I got off of Abilify and was put on Effexor. Since I got off the Abilify and switched to the Effexor I lost 50 pounds since February 8 2019! I also changed my diet and I am doing Keto. I feel absolutely amazing since changing my diet and my medication! I would definitely bring up getting off the Abilify to your doctor. There are many options and better medications out there that won’t make you gain weight. Good luck to you!
Hi! I’m not sure if anyone will respond (I hope someone does), but I’ve been off Abilify for a couple of months now and I still haven’t noticed any changes in my weight. I gained 66lbs in one year on abilify even when my eating pattern didn’t change much. I’m wondering if I will lose the weight again and how long it will take. I’m swimming 1h 3/4 times a week and I’m trying to eat only 1200 kcal a day. Hope someone can share their experiences! Thanks!
How are you doing since stopping Abilify? I stopped for two months, had a nervous breakdown and had to go back on it. I lost 20 pounds while being off it for those two months. However, as soon as I started back on it I gained those 20 pounds back in no time at all. So sorry to hear about the 66 pounds of weight gain, I too myself gained 70 on the drug. Terrible medication if I do say so myself. Good luck to you AliciaDl!
Hi Adamsmom! I’ve been really good. I went on it one year ago because of a psychosis and I’ve been off it for 3-4 months now. I feel fine and I haven’t had any withdrawal or psychotic symptoms. I really hope I can lose the weight but I’ve been working on it for 2 months now and nothing... I hope you’ll be ok! Maybe you can try another medicine? Something that makes you feel good and stable without the weight gain? Kind regards
Hi, mom! Yes, you will but it can take several months. Be aware that all antidepressants and anti-psychotics can cause weight gain in some people in case you're switching to another medication.
Yes you will lose most of the weight you gained while taking Abilify. I have taken 100 mg of Abilify in the past and gained 65 lbs rather quickly. When I stopped taking it I slowly got back to my normal weight. I decided that although it worked for my depression I could not stand being so fat and got off it. 3 months ago I again started taking Abilify as it was the only drug that worked for my depression. So far I have gained 50 lbs. Although I hate the weight gain it has made my depression so much better I am staying on it.
I have! It really depends on what you switch to after stopping abilify. I switched to seroquel and gained even more weight but then switched to Latuda and lost all the weight I gained plus some.
Thank you for your quick response. I am taking Prozac and I just weaned myself off of the Abilify, didn’t switch to anything different. Hope the weight comes off with good diet and exercise. ☺️
Related topics
abilify, depression, seizures, weight loss (obesity/overweight), weight
Further information
- Abilify uses and safety info
- Abilify prescribing info & package insert (for Health Professionals)
- Side effects of Abilify (detailed)
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