I would like to know if anyone is experiencing long term side effects. I was told I had Hep C and it was a shock. I have never engaged in any of the risk activities, never had a blood transfusion, never stuck a needle in myself etc etc. I took Epclusa 2 years ago and had mild side effects. I was later pronounced Hep C free. I now suffer from inflammation! From digestion problems to joint and muscle pain everywhere. No one can tell me what is wrong nor how to fix the issues. I feel sick and I can hardly walk from pain in my legs, back and hips. I wonder if it is from food, environment or if Epclusa could have trigged some kind of reaction in my body.
Long term side effects of drug Epclusa?
Question posted by jms57 on 21 Oct 2020
Last updated on 26 July 2023 by KrystleDeAnn
4 Answers
KrystleDeAnn
26 July 2023
I just couldn't believe what I was reading. I swear it feels like your living my life. I am experiencing the exact same health problems still even now after finished treatment over a year and a few months ago. I'm tired all the time even with taking my Adderall. Severe sharp painful headaches, naseau out of nowhere, the worst is when it rains omg I dread it. I get Severe burning pain in my legs my cavs and my.hands and feet swell up like balloons I've gotten no help from my specialist doctors they just take your.money I swear that's how it feels and your lucky if.tou get there full attention after having a 10mins appointment with them. The system is.so terrible. I had to go to the urgent care 5 times in 6 days I woke up at like 3am freaking out I literally from the top.of my head down to my feet completely covered in hives and rash they couldn't figure out why.
Still getting rashes they come and go and my feet and hands burn terrible along with my toes feels like I'm being electrocuted I can't even describe it it's just terrible then cramps on bottom of my feet and the lock up to where I can't even walk. I get blurry vision sometimes but ringing in my ears are the worst now because sometimes it won't stop for 2-3days strait it's awful and the abdominal pain is excruciating..theres.more.to but I'll stop there.for tonight. I've been doing my own research and have found out about alot.of medication issues with any kind of health diagnosis it's very concerning to me especially if u ever got the vaccine for covid.and the booster shot Worst mistake of my life
It's extremely upsetting and scary with what you should expext.to get after taking it. Cardiovascular issues,blurry vision, pulmonary embolism blod clots you can also get kidney and liver failure just from the vaccines.and booster sbot but then you add in your other medical issues you suffer from and it's like are.you serious it's plain right out a Nightmare!! Got to go talk tomorrow ok.
wellsmajor
9 May 2021
I contracted Hep C in Gaberones Africa from drinking at an hotel. All the classic signs on Hep C were apparent 6 weeks later. I do not engage in casual sex or take drugs. My Epclusa treatment finished 11 months ago and I also had leg pain and bad indigestion. My lingering side effects are that my abdomen swells occasionally and that my blood pressure is very high, which was not a problem before taking this drug. My gastroenterologist dodges the question and the manufacturer, when I asked the designated nurse to tell me how long I could expect side effects, read a 2 minute disclaimer and just told me that the drug should be out of my system by now. Trying to find out how it affects the body is difficult, but I get the impression that my liver is aggravated, but dont know what food if any may contribute to the problem.
LAM12
2 July 2022
8 months since I completed treatment with Epclusa. Same symptoms as you. I just don't feel like the same person as I was before Epclusa. Tired,sleepy,joint pain,hardness and tenderness after eating on right stomach side. Lumps under arms with shoulder pain is the oddest new thing. Dr. claims it will take at least 5 years for my fibrosis to get better! I was F 3 before treatment. Had no symptoms, lots of energy felt normal before treatment.
Hoping eventually all will get better
KatrinaWillard
27 April 2021
I also took Epclusa in 2016. I have all the symptoms that you are claiming and my doctor is done numerous blood test for arthritis, lupus, everything you can think of. I keep telling him it could have been a a side effect from Epclusa because I was totally fine before I started taking it and I've had severe blood pressure issues since. How many people have reported these symptoms?
KatrinaWillard
29 April 2021
Totally the same problem since 2016.. same tests done on me as well
LAM12
2 July 2022
Same. I've been trying to research what this Epclusa actually does to the body. I found it is the fact that the anti viral meds are protein inhibitors. This can cause lipase or fat elevation which in turn can cause all this inflammatory reaction that result in the joint pains, and weight changes etc. I had a difficult time controlling my blood pressure at end of treatment but now that is again under good control. My gastroenterologist told me it's likely going to take at least 5 years for fibrosis to clear. Hoping things evolve toward the better.
signguy1951
21 Oct 2020
I have been off Epclusa 2 years also, when i was on it had severe pain in legs also, i still have problems with legs, sore feel weak. Lost alot of hair that never came back, but it is what it is.
good luck
Fighter519
16 Jan 2021
Did you guys feel absolutely exhausted and depressed with Hep C? And did you feel better once treatment was through and side effects of mediicnes were gone?
Related topics
hepatitis c, side effect, blood, drug, risk, epclusa
Further information
- Epclusa uses and safety info
- Epclusa prescribing info & package insert (for Health Professionals)
- Side effects of Epclusa (detailed)
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