I would like to know if anyone is experiencing long term side effects. I was told I had Hep C and it was a shock. I have never engaged in any of the risk activities, never had a blood transfusion, never stuck a needle in myself etc etc. I took Epclusa 2 years ago and had mild side effects. I was later pronounced Hep C free. I now suffer from inflammation! From digestion problems to joint and muscle pain everywhere. No one can tell me what is wrong nor how to fix the issues. I feel sick and I can hardly walk from pain in my legs, back and hips. I wonder if it is from food, environment or if Epclusa could have trigged some kind of reaction in my body.
Long term side effects of drug Epclusa?
Question posted by jms57 on 21 Oct 2020
Last updated on 2 July 2022
I contracted Hep C in Gaberones Africa from drinking at an hotel. All the classic signs on Hep C were apparent 6 weeks later. I do not engage in casual sex or take drugs. My Epclusa treatment finished 11 months ago and I also had leg pain and bad indigestion. My lingering side effects are that my abdomen swells occasionally and that my blood pressure is very high, which was not a problem before taking this drug. My gastroenterologist dodges the question and the manufacturer, when I asked the designated nurse to tell me how long I could expect side effects, read a 2 minute disclaimer and just told me that the drug should be out of my system by now. Trying to find out how it affects the body is difficult, but I get the impression that my liver is aggravated, but dont know what food if any may contribute to the problem.
8 months since I completed treatment with Epclusa. Same symptoms as you. I just don't feel like the same person as I was before Epclusa. Tired,sleepy,joint pain,hardness and tenderness after eating on right stomach side. Lumps under arms with shoulder pain is the oddest new thing. Dr. claims it will take at least 5 years for my fibrosis to get better! I was F 3 before treatment. Had no symptoms, lots of energy felt normal before treatment.
Hoping eventually all will get better
I also took Epclusa in 2016. I have all the symptoms that you are claiming and my doctor is done numerous blood test for arthritis, lupus, everything you can think of. I keep telling him it could have been a a side effect from Epclusa because I was totally fine before I started taking it and I've had severe blood pressure issues since. How many people have reported these symptoms?
Totally the same problem since 2016.. same tests done on me as well
Same. I've been trying to research what this Epclusa actually does to the body. I found it is the fact that the anti viral meds are protein inhibitors. This can cause lipase or fat elevation which in turn can cause all this inflammatory reaction that result in the joint pains, and weight changes etc. I had a difficult time controlling my blood pressure at end of treatment but now that is again under good control. My gastroenterologist told me it's likely going to take at least 5 years for fibrosis to clear. Hoping things evolve toward the better.
I have been off Epclusa 2 years also, when i was on it had severe pain in legs also, i still have problems with legs, sore feel weak. Lost alot of hair that never came back, but it is what it is.
Did you guys feel absolutely exhausted and depressed with Hep C? And did you feel better once treatment was through and side effects of mediicnes were gone?
hepatitis c, side effect, blood, drug, risk, epclusa
- Epclusa uses and safety info
- Epclusa information for Healthcare Professionals (includes dosage details)
- Side effects of Epclusa (detailed)
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