I suffer MAJOR depression,and want to know,if these 2 meds are safe to take in combination.
Are you using Trazadone as a sleep aide or are you taking it as maintenance like I presume you are with the Zoloft? Nothing I have ever read or have I ever been told that these can not be taken together and I do A LOT of research. As with most of these types of medications that we take, we must use precaution until we know what the effects are on ourselves. Both of these drugs can cause drowsiness... mostly the Zoloft, so when combining medications one may exacerbate the side effects of the other. Case in point - myself - Zoloft made me almost non-functional... really not able to get off the floor. It did stop my panic attacks though!! I don't remember the strength. I hope this was helpful in some way.
I have taken the same combonation of meds in the past. No problem mixing them but I took the Zoloft in the AM and the tarazdone in the PM as it made me more drowsy. Hope this helps. If you dont seen an improvement in 3-4 weeks, you should talk to your DR. and make sure the doses are what you need. Side efects on both of these eased off real early for me also.
Yes sarajean. Perfectly safe. A very common side effect of zoloft is insommnia, all be it temporary. Most people to combat this take thier zoloft in the morning. And the trazodone is taken usually at bedtime because of its sedation qualities and so that in turn helps them get a nights sleep.
Sarajean, the only super negative problem with taking two SSRI's is Serotonin toxicity. Serotonin toxicity can be deadly. As far as hyperactivity with Zoloft is that SSRI may not be what your system needs. You may need an antidepressant that's not adding more Serotonin, to much is the most likely cause of why you feel up, as you say. With trazodone and Zoloft you're getting two Serotonin reuptakes. It's rare a Psychiatrist would risk prescribing two Serotonin SSRI's. He/ she may consider a sleep agent such as Ambien or Restoril for sleep as not to risk Serotonin toxicity. I see you asked your question long ago. Possibly someone can benefit from this information.
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