Met with a psychologist this morning. Turned out that I have definitely been reacting to the Ambien. He said it could take my body a few days to a few weeks to get over the withdrawal symptoms of the Ambien because of my medical history. I am off of that & since the Rozerem has not been working, he is switching me to Seroquel. He told me to try 25mg & if not enough to switch to 50mg & I might have to try 100, but feels that 25 or at most 50 should do the trick. Have any of you tried this & if so, how was it? Only planning on being on it long enough to get my sleep cycles back in track & then I am coming off of everything. He is also continuing me on Klonipin for the anxiety. We figured that a lot of this was brought on from long term use of Ambien. Any help concerning Seroquel would be extremely helpfull. Thanks in Advance... Tara
How much Seroquel should I take for sleep?
Question posted by taranallan on 2 Oct 2007
Last updated on 16 July 2022 by Itworks4me
9 Answers
Seroquel 400 to 800 MG with 10mg of Klonopin works perfectly for me. Sleeping 6 to 8 hours every night. Waking up to 12 oz of strong coffee and I am ready to go. I'm a partner in a Rep. Firm so if it didn't work, I would still be searching for my solution to the insomnia I've had. Without it and I can stay awake for days literally.
Why does sequel keep me awake?
New answer on an old thread about personal experiences of using Seroquel as a sleep aid. Short answer: the best dosage may be the least, particularly if you let go of the idea of a bullet-proof sleep. I was prescribed this drug a decade ago for early morning sleepless (2.00am - 5.00am), after having gone through the usual suspects. I was first prescribed 50mg, which laid me low for days after a single dose. I traded those in for 25mg pills, which laid me low for all of a day. I cut that pill in half to 12.5 mg which kept me asleep until 8.00am or 9.00am, after which I was dopey until about 3.00pm. This left me insufficiently functional , but the drug's consistent performance was appealing. It was only once I cut it in quarters (to 6.25 mg) that I found my sweet spot: enough to slip me into a pretty sound sleep most of the time until shortly before sunrise...
at which point I trained myself to lay there, relaxed about being awake then sometimes drifting back to some kind of slumber though not always. I wake up a big groggy but nothing that some yoga and a cup of joe can't remediate. Doubleplus good is that it doesn't seem to be the least bit addictive, and I don't seem to be suffering any cray-cray moments.
Seroquel is usually prescribed for sleep at the lower doses... 25mg to 50mg should be sufficient for a good night's sleep. Take more than that and you'll sleep alright... all night through the next day and night too!
Really depends on the person, (to the person who last posted Oct 2007), and whether you have had trauma.
If you are still having trouble sleeping I would suggest starting slowly with 50mg Trazodone increasing to 200 over a period of 9 to 12 months. Start with the 100mg Seroquel minimum. If that does not do it, add a 30mg Restoril Benzo. Take it about 30 minutes before you are ready to sleep.
I suffer from Major Chronic Insomnia (70 to 90 hours without sleep then maybe 6 to 8 hours of sleep and repeat).
After 8.5 years of trying pretty much everything, what works best for me is nightly : 100mg Seroquel mixed with a 30mg benzo called Restoril plus 6mg of another benzo called Klonopin plus 300mg trazodone plus 600mg Lithium LiCO3 and finally top it off with 1 to 2 7.5mg Norco. This combination gives me about 8 hours sleep. I do have to use 90mg Adderall when I wake up to get rid of the dizziness, vertigo, poor depth perception, and slow response time.
Yes... I know that sounds impossible but my respatory system handles it pretty good. My average O2 stats are 88-90 which is classified as Anemic (your O2 should be 98-100).
I tried Ambien (10mg) but that did nothing for me. And never mix Ambien with Restoril! Your respatory system would most likely shut down while you sleep.
Seroquel is offered in 25, 50, 100, 200, 300, and 400. 25 & 50 are worthless.
That should be determined by your doctor.
Seroquel is an interesting drug. I have been using it for about 2 years. Dosges are strange in their effects. I was prescribed seroquel at the amount of 50mg. to start, I am bipolar. But this was a new drug for me, after 20 years on one regime of drugs sometimes they are no longer as effective and in my case were starting to have serious adverse effects. Nevertheless it worked okay, but i was also on nightshift and soon enough i was taking 450mg, 50mg, during the day, and 400mg to sleep at 3:00pm in the afternoon. It worked, but it took awhile before that dosage had bad side effects. EXTREME sweating, 3 hours into sleep I would wake paniced and dripping wet, hair even inbetween my toes. It was terrible and therefore couldn't sleep. And extreme heart palpitations. I had to quite working that shift and stop taking 400mg of seroquel. I am now back at 50mg. and it is working, but I have the palpitation side effect, it is uncomfortable.
What happened next was once my body switched back to sleeping in the night, the 400mg dosage of seroquel gave me hullucinations. So dosage, yes 50mg. don't go higher. From my experience if this doesn't help you sleep, stop and change meds.
Hi there!
Saw your call for help so i hope i can! My husband has been taking seroquel for the past year and a half. He suffers with schizophrenia. After having severe panic attacks and delusions that someone was out to get (kill) him, really terrible nightmares and sleep lost not to mention the bad diagnoses which led to drugs that caused facial spasms and seisures he eventually came right on 600mg of seroquel. Its uses are varied so dont worry im not saying you have Schiz!!! This drug effects everyone differently but the main side effects are a sedative effect which is obviously what you are after. Although if you suffer with weight gain watch out as this drug severly increases your appetite! Women are known to put on a lot of weight and the down side to this is that you may become depressed about it! Seroquel will definately help with your panic attacks although you may have to ride it out for a while and see if you need to increase your dosage.
The bottom line is no matter what drug you take now there will be side effects and you have to weight this up. I have done extensive research on this drug and although fairly new to the market and the fact that they really dont know how it works, it seems to be fairly safe comparing some of the other drugs out there.
I want you to know that I understand something of what you are going through and I know that it can be life consuming. I really hope that seroquel works for you! At least to help you sleep as I know personally what sleep deprived minds think & feel. All the best - Lee.
I have tried seroquel, you should only need 25 to 50 because it will knock you right out. lol. Anything higher than that will keep you sleepy the next day.
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Further information
- Seroquel uses and safety info
- Seroquel prescribing info & package insert (for Health Professionals)
- Side effects of Seroquel (detailed)
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