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How long does Prednisone stay in you system after you quit taking it?

This question has also been asked and answered here: How long does prednisone stay in your system for... I have bronchitis?

Responses (3)

oktoday 18 Feb 2010

the half life is roughly 4 hours. The prednisone should be tapered slowly and never stopped abruptly if you have been on it for over 2 weeks and were are a high dose. if you took it for 2-3 days you should be fine. The higher the dose and the longer you are on the drug the slower the taper. The drug itself should be out of your body less than 24 hours but flair ups can result if not tapered. Hope this helps.

suzanne66 14 Jun 2011

The elimination half life of prednisone is around 3 to 4 hours. This is the time it takes for your body to reduce the plasma levels by half.
It usually takes around 5.5 half lives for a drug to be completely eliminated from your system.
With that in mind you could expect a dose or prednisone to be out of your system 16.5 to 22 hours later.
Other factors also need to be taken into account and include:
1. How much and how often you have taken the drug.
2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
4. Body mass – generally the bigger you are the longer a drug will remain in your system.
Hope this is of help.


Jean freeman 5 days ago

Yes I would like a direct answer to my question! I was prescribed 20 mg Prednisone, for bronchitis, x 10 day supply (I have asthma), I also worked as a pharmacy technician for 12 years. I left my job due to , health, issue. free discount card

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