I am on week 2 of an increase from 20 mg to 40 mg of Prozac for depression. I only took the 20 mg dosage for 2 weeks. Before then, I had been on Pristiq for 9 months. I am experiencing a dizzy feeling in my head accompanied by a warm, tingling sensation, dilated pupils, shakiness, among other things. I wake up around 4 or 5 a.m. with this feeling, and I felt very alarmed the first day this happened. I called my prescribing doctor, but she was sure these side effects aren't from Prozac. Has anyone experienced something similar? Is it worth sticking with Prozac? I have unsuccessfully taken Pristiq (raised my blood pressure too much), Lexapro, and Cymbalta. I liked Trintellix, but my insurance will not pay for it.