That is one of the side effects for that class of drugs.
I take another version of that drug called Nortriptyline for prevention of migraines. Yes, I have noticed weight gain also. It's one of those things you just have to weigh the side effects against the the good it will do you. Although I am going to stop taking this drug as soon as I can.
Amitriptyline side affects include weight gain. I found this out the hard way - after I gained 15 pounds. It reduces your metabolism, makes you crave creamy, high fat foods and increases your appetite. Once I knew that, I was able to get the weight gain under control.
I never realized that it could make you gain weight until I read some of these answers. WOW what an eye opener for me. I was wondering why I was gaining weight when I don't do anything but throw up alot due to cancer issues right now. I am on 50mg at bedtime and have actually gained some weight back I really didn't want to but I did and this seems to explain why. I will mention it to the doctor because they couldn't figure out why I was gaining now. Thanks guys you have helped in a way you may not know.
I've been on amitriptyline for years with NO weight gain & NO side effects. I had been taking the generic made by Qualitest Pharmaceuticals for years & never gained an ounce and had NO side effects for years. Then the mail order pharmacy sent me a generic made by Sandoz Inc. I gained TONS of weight in less than 4 months and I had nearly every side effect on the list! But I didn't know they were side effects. I thought I was sick. I went to many Doctors because in addition to the weight gain, I felt very, very sick. I thought I must have had a stomach tumor as I was so swelled up and in so much pain (even had an ultrasound.) Then, I had to take meds for vertigo (severe unexplained dizziness,) and meds for severe reflux (heartburn.) I even went to the eye doctor for blurred vision and got steroid eye drops! I had tons of costly tests. Finally, I figured it out myself.
All of my problems were identical to the side effects of amitriptyline. It was not a coincidence. Guess what? Nothing was wrong with me! Specifically, it was the amitriptyline made by Sandoz Inc because the problems all began when I started taking the Sandoz Inc generic and they all went away when I switched back to the Qualitest Pharmaceuticals generic. About 2 wks ago, I stopped the Sandoz Inc. generic and went back to the Qualitest Pharmaceuticals generic. I've already lost 7 lbs and all of my problems have disappeared. I don't need any of the other medication (which was treating my side effects.) ALL GENERICS AREN'T THE SAME. Try a generic made by a different company. The Qualitest Pharmaceuticals generic works the best for me! NO weight gain and NO side effects! I feel great again! All pharmacies carry generics made by different companies. Try a different generic. The pharmacy will tell you who makes the generic that they carry - call all the pharmacies first! You won't believe the difference. I hear It's different for everyone though. The generic that works best for me may not be the same as the generic that works best for you. But I swear by Qualitest Pharmaceuticals! I was taking tons of meds (to treat SIDE EFFECTS.) I wasn't even sick! Ask your doctor! Read up on it! It's true! Best of luck!
Yes, I sure did, 20lbs and I could have kept going. I just weaned off finally from 50 mg to 25mg and then just stopped. Now I'm hoping to see the lbs melt off.
Hi i guess i was one of the luck ones, i didn't gain any weight or get any bad side effects
this is just one of the side effects (or should I say effects of this particular group of drugs
I have been on a high dose of amitriptyline (150 mg) for over a yeah and I have gained a huge amount of weight.I have always weighed between 53-55kgs except when pregnant.I now weigh 82 kgs.I have very strong cravings for sweets.its a real struggle not to eat them.I had to go to my doctor to try and get off it.I'm on it because of bad post natal depression and even worse anxiety.I can't stay on endep because I'm becoming more and more depressed about my weight.I near kill myself with yoga and the treadmill only to lose 2kgs... from what I've learnt low doses of this Med doesn't case weight gain.I am also really tired all the time...
I have been taking ammo for years for neuropathic pain in my amputated leg, but after a few ops, I was able to come off all meds and the weight just dropped off alarmingly. From 94kg to 80kg. However, the pain returned with a vengeance and I went back on ammo but three times the dosage and I have put 5kg on since Nov 2015. Very disappointed because it was a novelty to feel my rib cage.
I am here because I have the same question. I have been taking 20 mg for five years and about every few days I have a voracious appetite which is unpleasant. I take this for esophageal spasm pain and it is a necessary med for me, but my gastroenterologist says 20 mg will not increase my appetite. Does any other 20 mg peeps have this problem?
Yes, significantly! I am normally a size 2-4, even size 6. I have gained about 70 lbs, I crave breads like they are going out of style and my normal sweet tooth has been increased by 3-4x. But it significantly helps my Neuralgia, stress and sleep. So I am not quite ready to do anything about my weight, The rest of my diet consists mostly of veggies and cheese.
When I was younger (20's?), I was STARTED on 125mg for sleep and migraines. Over the next 20 years, I gained over 100 pounds AND became diabetic. After we realized that it was the only "stable" factor that hadn't changed (we were trying to explain the weight gain), I came off and lost 100# in 9 months.
Doctors have told me patients ask to be taken off when people gain 5 pounds at much lower doses.
A few months ago, I agreed to start back on an extremely low dose (25mg) because it's the only med that provides the sleep I need. I insist on being weighed at every meeting (monthly) and up until last month, everything was going fine.
When I hit 50-75mg, I noticed my weight and blood sugar starting to rise. I'm hoping it can be controlled without stopping the drug completely, but it was understood at the start that I was hesitant to "try."
I'm assuming I'll be decreasing doses until I can transfer to something else. It's frustrating, because I've had sleep problems all my life and found the only 100% cure after 3 nights of 1/4 tsp of medical marijuana oil. I had been on 200mg of trazodone after moving from Elavil, and had been off all medications (except the oil at bedtime) for 4 years.
Now that I'm in a "non-legal" state, I'm back on 3 medications and I don't like it at all.
I have been on Amitriptyline 25 mg for years, without much weight gain. My doctor has recently been increasing my amount for migraines and now I'm on 100 mg daily. I have gained 50lbs since October and I hate it. Luckily I have an appointment with my doctor this week and am going to see what else I can take that doesn't cause weight gain. With working with a nutritionist and on 1400 cal a day I knew something else was going on. Glad I finally found the possible culprit.
I have!!! i use 25mg for migraines and i gained 20 pounds since 6 months !! i used to weigh 110, vegan, run everyday so healthy. and i weigh 130 pounds and am so bloated!! my period is also messed up.. i stopped the pill but if i stop it will i lose all the weight i gained right away??
- Amitriptyline Information for Consumers
- Amitriptyline Information for Healthcare Professionals (includes dosage details)
- Side Effects of Amitriptyline (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.