Hi Everyone & Bless u all! I take Wellbutrin 150 mg SR & my dear brother take 300 mg XL. I was wondering if you guys take it on an empty stomach or after eating a meal? I like 2 take the wellbutrin before I leave to go to work or on weekends later, as I wake up later on weekends. Do you guys feel a difference when taking it on a full stomach as opposed to a empty stomach? I find that the Wellbutrin SR gives me energy & I feel more alert & enthusiastic, so I am glad that my therapist recommended it to me! What do u guys think about taking on an empty stomach? Thanks for your replies & God bless u!