read the comments on wellbutrin xl on this site, one comment suggested getting wellbutrin, more $$? have very mild depression and adult ADHD. met with doctor today and when i picked up medication was burporpion, subsitute for Wellbutrin. so started investigating before i get started. appreciate the comments.
Is there a difference between bupropion hcl xl and wellbutrin xl?
Question posted by scott22 on 11 June 2014
Last updated on 10 August 2016 by joearnold555
the difference between wellbutrion xl and wellbutrion xl hcl
2 posts above this is a very good and comprehensive reply about generics being equivalent to the original branded drug. But that is in theory. In practice it has been a very different story. Take for example bupropion xl 300mg. It was on the market 6 years before the FDA was forced to admit it never checked the bioequivalence of the drug. Yes same amount fo active ingredient, but the way they made the tablet meant it didn't release the ingredient any more than a 150mg...
All fixed now aparently and they FDA say the have updated the protocols for dtermining bioequivalence, rather than guessing, whcih is in effect what hapenned in this case.
Lots of media reports on this one, including a good one in new York time, see fda rlupdates here: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm322161.htm
Hi, Scott! Generics do contain exactly the same drug as the brand names, but they are allowed to contain anywhere from 80 - 125% of the drug.
On occasion, I've found that one generic doesn't seem quite the same as the last; this is because most pharmacies will re-stock with the least expensive to keep your costs down.
It you find that happens to you, you can ask your pharmacist to special order the one you liked. It may cost a tad more, but being generics it's never cost me more that a dollar or two.
Best wishwes, WCV
Nothing much. One (Wellbutrin) is a brand name. Bupropion is a generic name. The active ingredients are the exact same but the inert (non active) ingredients can be different.
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