I know a lot of medications have many companies that make generics of the medicine. I know that the original Norco and most of the generic Norco are yellow in color. I found 2 white pills that look exactly the same and when searched the imprints on them, they were identified as generic Norco - 10mg hydrocodone/325 acetaminophen. The tablets, even though they look alike in color, size, and shape, have only one difference: the imprints. One of the tablets has "M367" on one side and just a line down the middle on the other side for easy breaking. The other pill, looking exactly the same, has the imprint "M523" on one side and no line on the other side, but another imprint of "10/325." Are these both really generic Norco (10 hydro/325 apap)? And if so, what is the difference between these 2 tablets/medications?
17 Nov 2012
I disagree. I know they're supposed to be the same but myself and someone else I know with chronic pain, have noticed a remarkable difference lately. The white ones are not nearly as strong and seem to make me jittery. When both of us have mentioned this to each of our pharmacists we were laughed at and told that it was impossible. We now go to pharmacies that consistently use the yellow ones. I'd love to know how this could happen and how to get pharmacy to believe me. I'm spending a lot more now by not going the warehouse store.
10 May 2013
Pharmacists say this is the same drug, regardless of color. However, having been on this drug myself I agree with all the others who say that the yellow pill seems to pack more punch to it, while the white seems weaker. It is supposedly not true, but it has been what I have experienced also
12 May 2013
Yes they are the same drugs. I used both types on many occasions over the years, and I also found the yellow ones to be slightly stronger. I believe it is because the manufacturers have certain allowed tolerance levels as to how much active ingredient must be included in the drug. This means they are allowed certain deviation from the standard amount, plus minus certain percentage. For example, one manufacturer might be putting plus 15% of hydrocodone above the standard and the other might be putting minus 10 % of hydrocodone below the standard. Both are within the allowed tolerance but this can mean a 25% difference between the amount of active ingredient in the pills from one over the other manufacturer.
Another observation I has is that the yellow pills always seem to be much fresher. You can almost smell the difference when you open the bottle. I am not sure why that is but it seems as the pharmacies store the white pills for much longer time and the yellows pills always seem as recently manufactured. I have to say this is the case most of the times. but I did also have a case on one occasion where the yellow pills were not so much different from the white ones.
19 Oct 2014
I agree that there is a difference. I have been using white for years, I was changed to yellow of the same dosage. I only take one pill. I took one of the yellow, it was too strong for me. I had a slight headache too. I broke it in half, and all was well. There is definitely a difference, I don't care what the pharmaceuticals say. They need check further.
19 Nov 2014
This is more of a statement & opinion, than a direct answer.
How many agree with what I am going to say here?
I have been prescribed Norco 10/325 tablets, for quite awhile now. I just yesterday got a new Rx & new pain management center and physician, as well.
Note: occasionally I will ask for Percocet, so my body can have something slightly different. A change is a good idea, once in awhile... since your system can get too use to a certain medication.
Anyway, I have noticed for a long time now, that their is definitely a difference in quality & potency between different generic drug companies.
I very much believe that the Qualitest brand, is THE best out there! They are a yellow tablet with a stylized "V" on one side & "36 | 01" on the other side. These very much seem to work the best, out of all the generics out there.
The white ones from other companies just don't work as well, for me. I have heard other people say the same thing.
Safeway pharmacy is where I can get these. In fact, they ran out of the yellow ones a few months ago, & I had to get the white ones. Their was such a huge difference in potency & effectiveness.
Just a tip, for patients prescribed Vicodin/Norco. Their IS a difference in generic drug companies!! I hope this helps.
Ps- I know their is a rating for the different generics they make, for all or most medication. Eg, "AB," etc. I almost forgot about the letters ratings, until recently. I actually forgot how that system works.
I hope I have helped some people that use generic Vicodin!
24 May 2015
It's definitely not a coincidence, especially when you have hundreds of people that agree that the yellow ones are stronger. I my self agree with the masses that they are stronger. Especially than the white 367s, I've come to a conclusion after some research on the FDAs web site. I don't have the link but if you search FDA guide lines for norco in Google you will find it. The FDA allows norco manufacturers a pretty big difference on the hydro. As long as the manufacturer is + or - 15% of the 10 mg of the good stuff they are ok. Which I think is bull because the manufacturer can sell 10s, and you could be getting only a 8.5. Which would explain the difference in strengths of the same drug just different manufacturers. I believe the manufacturers of the yellow ones are on the higher side of the guidelines, and the white ones are on the lower side. Just think there can be a 30% difference by law and they can get away with selling it to us. Just my two cents, and only my opinion
15 Dec 2015
If you are a chronic pain suffer and take these meds multiple times a day everyday for years you can tell a huge difference! I plan what I do everyday around the time I take my medication as I know my yellow norco would kick in and I could physically get things done in a certain time frame. With the white ones, I can't tell I have taken anything. I would bet my life there is SOMETHING very different. The yellow norco are not time released. I can not take anything time released because it bypasses my system to quickly and I do not get anything out of them. Maybe the white are time released and it goes right through me. It really insults my intelligence that the companies and pharmacies tell me there is no difference and I'm furious I have to spend a whole month in pain when I am given the white ones. I will start asking what color the pharmacy has before I get them filled again. I refuse to live in pain and get ripped off.
27 Mar 2016
I'm so glad I found this site and some sanity! I agree the white tabs are almost useless. Is anyone having any luck with the orange ones? I had to change from Walgreens because they never had my meds in stock and had to order which could take up to two weeks. The individually owned pharmacy I use now has the orange. They seem to be as bad or worse than the white. My doc decided to cut me two 2 tabs a day so I need this stuff to work!
1 Jun 2016
Yes the Watson brand are most certainly the most effective. I literally had to take 2 of the white norcos to get the same relief. The pharmacists that tell you otherwise are ignorant. I've taken all kinds of narcotic pain medications 5mg,7.5mg, and 10mg of hydro AND oxycodone. "Qualitest" or whatever the norcos with the V are second best. The "Malinkroft" or as i call them "Malinkrap" m367s, m366s are garbage. DO NOT WASTE YOUR MONEY ON THEM SO THEY START PUTTING THE CORRECT AMOUNT OF PAIN MEDICATION IN THEM OR LET THEM GO OUT OF BUSINESS. Perfect example of American greed for ya, cutting corners on the elderly and chronic pain sufferers to turn a profit. Makes my blood boil... I've been stuck whole months suffering with them generics so I can empathize...
- Norco Information for Consumers
- Norco Information for Healthcare Professionals (includes dosage details)
- Side Effects of Norco (detailed)
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