I have been experiencing chronic muscle pain in my arms, legs, and back for a period of time that might correlate with my time using trazodone.
Can Trazodone cause chronic muscle ache/pain/fatique?
Question posted by printer1 on 27 Feb 2010
Last updated on 9 July 2025
Are there any studies/data that detail how commonly the above issue occurs?
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Answers Page 3
I found this information that adresses your problem.
"most COMMON side effects persist or become bothersome when using Trazodone:
Blurred vision; constipation; decreased appetite; dizziness; drowsiness; dry mouth; general body discomfort; headache; incoordination; light-headedness; muscle aches/pains; nausea; nervousness; sleeplessness; stomach pain; stuffy nose; swelling of the skin; tiredness; tremors."
I reviewed my medial notes and I started to see my doctor's much more frequently for muscle and bone pain... this went on for 3.5 years and I have to say that many of these side effects were resolved when I discontinued trazodone.
Thanks so very much for the information! Those are the exact symptoms that I have. Time for me to taper off of Trazodone as it is destroying me! I don't, however, get headaches or nausea, itsmetoo2. Thank you again! I seriously must get off of this medication. As I write I am dizzy, have blurred vision, have horrendous muscle aches and pains, and am feeling very nervous! I am exhausted, as well!
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Further information
- Trazodone uses and safety info
- Trazodone prescribing info & package insert (for Health Professionals)
- Side effects of Trazodone (detailed)
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